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  1. Article

    Open Access

    Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer

    Cancer cells sustain their metabolic needs through nutrients and oxygen supplied by the bloodstream. The requirement for tumor angiogenesis has been therapeutically exploited in the clinical setting mainly by ...

    Matteo Bocci, Jonas Sjölund, Ewa Kurzejamska, David Lindgren… in Angiogenesis (2019)

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  2. Article

    Open Access

    Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

    Cancer-associated fibroblasts (CAFs) are a major constituent of the tumor microenvironment, although their origin and roles in sha** disease initiation, progression and treatment response remain unclear due ...

    Michael Bartoschek, Nikolay Oskolkov, Matteo Bocci, John Lövrot… in Nature Communications (2018)

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  3. No Access

    Article

    Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling

    Paracrine signaling networks in the breast cancer microenvironment uncover determinants of hormone receptor status and offer opportunities for therapeutic intervention.

    Pernilla Roswall, Matteo Bocci, Michael Bartoschek, Hong Li… in Nature Medicine (2018)