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Open AccessEpigenetic control of chromosome-associated lncRNA genes essential for replication and stability
ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis. The three known ASAR genes are located on human chromosomes 6 and 15, and are essential for chromosome int...
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Open AccessPatient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours
Cancer development is presumed to be an evolutionary process that is influenced by genetic background and environment. In laboratory animals, genetics and environment are variables that can largely be held con...
