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Article
Open AccessAuthor Correction: Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
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Article
AAV/BBB-Mediated Gene Transfer of CHIP Attenuates Brain Injury Following Experimental Intracerebral Hemorrhage
Cell death is a hallmark of secondary brain injury following intracerebral hemorrhage (ICH). The E3 ligase CHIP has been reported to play a key role in mediating necroptosis—an important mechanism of cell deat...
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Article
Open AccessAnisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
Necroptosis is an essential pathophysiological process in cerebral ischemia-related diseases. Therefore, targeting necroptosis may prevent cell death and provide a much-needed therapy. Ansiomycin is an inhibit...
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Article
Association of GWAS-Reported Variant rs11196288 near HABP2 with Ischemic Stroke in Chinese Han Population
A recent genome-wide association analysis identified a novel single nucleotide polymorphism locus on chromosome 10q25.3 (rs11196288, near HABP2) associated with the risk of early-onset ischemic stroke (IS) in Eur...
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Article
Open AccessNecroptosis in neurodegenerative diseases: a potential therapeutic target
Neurodegenerative diseases are a group of chronic progressive disorders characterized by neuronal loss. Necroptosis, a recently discovered form of programmed cell death, is a cell death mechanism that has necr...
