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  1. Article

    Open Access

    The moderating effect of prefrontal response to sleep-related stimuli on the association between depression and sleep disturbance in insomnia disorder

    We investigated differences in brain activity in response to sleep-related pictures between chronic insomnia disorder (CID) patients and good sleepers (GS), and examined whether brain activity moderated the re...

    Mi Hyun Lee, Kyung Hwa Lee, Seong Min Oh, Min Cheol Seo, Hayoung Lee in Scientific Reports (2022)

  2. Article

    Open Access

    Multitask fMRI and machine learning approach improve prediction of differential brain activity pattern in patients with insomnia disorder

    We investigated the differential spatial covariance pattern of blood oxygen level-dependent (BOLD) responses to single-task and multitask functional magnetic resonance imaging (fMRI) between patients with psyc...

    Mi Hyun Lee, Nambeom Kim, Jaeeun Yoo, Hang-Keun Kim, Young-Don Son in Scientific Reports (2021)

  3. Article

    Open Access

    The TLR-2/TonEBP signaling pathway regulates 29-kDa fibronectin fragment-dependent expression of matrix metalloproteinases

    Tonicity-responsive enhancer-binding protein (TonEBP; nuclear factor of activated T cells 5) is a transcription factor that responds to changes in osmolality. However, recent studies have shown that it also mo...

    Hyun Sook Hwang, Mi Hyun Lee, Hyun Ah Kim in Scientific Reports (2021)

  4. Article

    Open Access

    MicroRNA-365 regulates IL-1β-induced catabolic factor expression by targeting HIF-2α in primary chondrocytes

    Endothelial Per-Arnt-Sim domain protein-1/hypoxia-inducible factor-2α (EPAS-1/ HIF-2α) is a catabolic transcription factor that regulates osteoarthritis (OA)-related cartilage destruction. Here, we examined wh...

    Hyun Sook Hwang, Su ** Park, Mi Hyun Lee, Hyun Ah Kim in Scientific Reports (2017)