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  1. No Access

    Article

    Quetiapine improves sensorimotor gating deficit in a sleep deprivation-induced rat model

    Sleep deprivation (SD) impairs pre-stimulus inhibition, but the effect of quetiapine (QET) remains largely unknown.

    Öznur Özge Özcan, Burcu Çevreli, Arzu Temizyürek… in Sleep and Biological Rhythms (2024)

  2. Article

    Open Access

    In silico analysis of missense SNPs in GABRA1, GABRB1, and GABRB3 genes associated with some diseases in neurodevelopmental disorders

    Neurodevelopmental disorders are disorders that are generally seen in the early developmental period of an individual's life and involve more than one disease that causes disruptions in the central nervous sys...

    Mehmet Manaz, Ömer Faruk Karasakal… in Egyptian Journal of Medical Human Genetics (2023)

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    Chapter

    Role of Antioxidants, and Lifestyle in Managing Brain Disorders Oxidative Stress Biomarkers and Antioxidant Treatments in Brain Diseases

    Currently, research continues on the stage of the disease and the biological characteristics of oxidative stress, which occurs at the molecular level in the neuropathophysiology of neuropsychiatric disorders. ...

    Öznur Özge Özcan, Mesut Karahan… in The Role of Natural Antioxidants in Brain … (2023)

  4. No Access

    Article

    Synthesis, Characterization and Lipophilicity Study of Brucella abortus’ Immunogenic Peptide Sequence That Can Be Used in the Future Vaccination Studies

    Brucellosis is primarily a zoonotic disease caused by members of the Brucella genus which consists of 11 recognized species based on pathogenicity and host preferences. Peptide vaccines are an alternative stra...

    Tayfun Acar, Pelin Pelit Arayıcı, Burcu Ucar… in International Journal of Peptide Research … (2019)

  5. Article

    Development of Vaccine Prototype Against Zika Virus Disease of Peptide-Loaded PLGA Nanoparticles and Evaluation of Cytotoxicity

    Zika virus has recently evolved from an obscure mosquito-borne pathogen to an international public health concern. People with Zika virus disease can have indications including mild fever, skin rash, conjuncti...

    Fulya Çalman, Pelin Pelit Arayıcı… in International Journal of Peptide Research … (2019)

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  6. No Access

    Article

    Radiation shielding parameters of some antioxidants using Monte Carlo method

    In this paper, radiation shielding parameters such as mass attenuation coefficients and half value layer (HVL) of some antioxidants are investigated using MCNPX (version 2.4.0). The validation of the generated...

    Huseyin Ozan Tekin, Mesut Karahan, Turker Tekin Erguzel… in Journal of Biological Physics (2018)

  7. No Access

    Article

    Synthesis, structural characterization, and antiproliferative/cytotoxic effects of a novel modified poly(maleic anhydride-co-vinyl acetate)/doxorubicin conjugate

    Drug carrier, poly(maleic anhydride-co-vinyl acetate) (MAVA or poly[MA-co-VA]) copolymer, was traditionally synthesized by free radical chain polymerization reaction, in methyl ethyl ketone (MEK) organic media at...

    Gulderen Karakus, Abdulilah Ece, Ayse Sahin Yaglioglu… in Polymer Bulletin (2017)

  8. No Access

    Article

    Investigation of Ternary Complex Formations of Polyacrylic Acid with Bovine Serum Albumin in the Presence of Metal Ions by Fluorescence and Dynamic Light Scattering Measurements

    In this paper, the complex formation of bovine serum albumin (BSA) and polyacrylic acid (PAA) in the presence metal ions at pH = 7 has been examined by using fluorescence and dynamic light scattering measureme...

    Mesut Karahan, Zeynep Mustafaeva, Cemal Özeroğlu in The Protein Journal (2010)