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  1. Article

    Open Access

    Posterior scleral birefringence measured by triple-input polarization-sensitive imaging as a biomarker of myopia progression

    In myopic eyes, pathological remodelling of collagen in the posterior sclera has mostly been observed ex vivo. Here we report the development of triple-input polarization-sensitive optical coherence tomography...

    **nyu Liu, Liqin Jiang, Mengyuan Ke, Ian A. Sigal in Nature Biomedical Engineering (2023)

  2. No Access

    Article

    Anterior Segment Optical Coherence Tomography Angiography Assessment of Corneal Vascularisation After Combined Fine-Needle Diathermy with Subconjunctival Ranibizumab: A Pilot Study

    To describe anterior segment optical coherence tomography angiography (AS-OCTA) imaging to monitor corneal vascularisation (CoNV) and scar reduction after combined fine-needle diathermy (FND) with subconjuncti...

    Valencia Hui **an Foo, Mengyuan Ke, Chelsea Qiu Lin Tan in Advances in Therapy (2021)

  3. Article

    Open Access

    Choriocapillaris microvasculature dysfunction in systemic hypertension

    We examined the choriocapillaris microvasculature using a non-invasive swept-source optical coherence tomography angiography (SS-OCTA) in 41 healthy controls and 71 hypertensive patients and determined possibl...

    Jacqueline Chua, Thu-Thao Le, Bingyao Tan, Mengyuan Ke, Chi Li in Scientific Reports (2021)

  4. Article

    Open Access

    A pilot study investigating anterior segment optical coherence tomography angiography as a non-invasive tool in evaluating corneal vascularisation

    The current assessment of corneal vascularisation (CV) relies on slit-lamp examination, which may be subjective. Dye-based angiographies, like indocyanine green angiography (ICGA), allows for good visualisatio...

    Hon Shing Ong, Kai Yuan Tey, Mengyuan Ke, Bingyao Tan in Scientific Reports (2021)

  5. Article

    Open Access

    Effect of vessel enhancement filters on the repeatability of measurements obtained from widefield swept-source optical coherence tomography angiography

    We assessed the inter-visit repeatability of 15 × 9-mm2 swept-source OCTA (SS-OCTA; PLEX Elite 9000, Carl Zeiss Meditec) metrics in 14 healthy participants. We analysed the perfusion density (PD) of large vessels...

    Jimmy Hong, Mengyuan Ke, Bingyao Tan, Amanda Lau, Damon Wong in Scientific Reports (2020)

  6. Article

    Open Access

    Retinal microvasculature dysfunction is associated with Alzheimer’s disease and mild cognitive impairment

    The retina and brain share many neuronal and vasculature characteristics. We investigated the retinal microvasculature in Alzheimer’s disease (AD) and mild cognitive impairment (MCI) using optical coherence to...

    Jacqueline Chua, Qinglan Hu, Mengyuan Ke, Bingyao Tan in Alzheimer's Research & Therapy (2020)

  7. Article

    Open Access

    Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study

    We evaluated the impact of diurnal variation on choroidal and retinal microvasculature and structural measurements using a swept-source optical coherence tomography angiography machine (SS-OCTA; PLEX Elite 9,0...

    Emily Lin, Mengyuan Ke, Bingyao Tan, **nwen Yao, Damon Wong in Scientific Reports (2020)