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Article
Open AccessAssociation of potentially inappropriate medications with prognosis among older patients with non-small cell lung cancer
Potentially inappropriate medications (PIMs) are common among older adults with cancer, but their association with overall survival (OS) among non-small cell lung cancer (NSCLC) patients remains unclear. This ...
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Article
Open AccessPotentially inappropriate medications among older patients with Parkinson’s disease: a cross-sectional analysis of a national health insurance database in China
With the rapid aging trend of China's population, the issue of drug rational use in older adults has become more and more prominent. Parkinson’s disease (PD) is the one of the most common age-related neurodege...
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Article
FBXL2 promotes E47 protein instability to inhibit breast cancer stemness and paclitaxel resistance
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a high risk of metastasis and recurrence. Although chemotherapy has greatly improved the clinical outcome of TNBC patie...
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Article
Open AccessCorrection: E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
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Article
Open AccessFBXL2 counteracts Grp94 to destabilize EGFR and inhibit EGFR-driven NSCLC growth
Abnormal activation of epidermal growth factor receptor (EGFR) drives non-small cell lung cancer (NSCLC) development. EGFR mutations-mediated resistance to tyrosine-kinase inhibitors (TKIs) is a major hurdle f...
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Article
Open AccessAntibiotic use and irrational antibiotic prescriptions in 66 primary healthcare institutions in Bei**g City, China, 2015–2018
To identify the patterns of antibiotic use and irrational antibiotic prescriptions in primary healthcare institutions (PHIs) in Dongcheng District of Bei**g, China.
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Article
Open AccessOutpatient prescribing pattern for acute bronchitis in primary healthcare settings in China
Inappropriate prescribing for acute bronchitis in primary healthcare settings (PHSs) is commonly seen worldwide. Here we describe the prescribing patterns and antibiotic use for acute bronchitis in PHSs across...
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Article
Open AccessE47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
Targeted therapy has greatly improved both survival and prognosis of cancer patients. However, while therapeutic treatment of adenocarcinoma has been advanced greatly, progress in treatment of squamous cell ca...
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Article
Open AccessSecular trend analysis of antibiotic utilisation in China’s hospitals 2011–2018, a retrospective analysis of procurement data
This study was aimed to explore the secular trends of antibiotic utilisation in China’s hospitals over an 8-year period.