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  1. Article

    Open Access

    C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule

    The precise modification or functionalization of the protein C-terminus is essential but full of challenges. Herein, a chemical approach to modify the C-terminus is developed by fusing a cysteine protease doma...

    Yue Zeng, Wei Shi, Zhi Liu, Hao Xu, Liya Liu, Jiaying Hang in Nature Communications (2023)