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    The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via induction of pyroptosis

    Gastric cancer (GC) is a deadly disease with poor overall survival and limited therapeutic options. Genetic alterations such as mutations and/or deletions in chromatin remodeling gene AT-rich interactive domai...

    Menghan Fang, Youfen Lin, Chaorong Xue, Kaiqin Sheng in British Journal of Cancer (2024)