-
Article
Human genetics special issue on computational molecular medicine
-
Article
Open AccessA comparative encyclopedia of DNA elements in the mouse genome
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To gain greater in...
-
Article
Open AccessExploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser
The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu) offers interactive visualization and exploration of TCGA genomic, phenotypic and clinical d...
-
Article
An encyclopedia of mouse DNA elements (Mouse ENCODE)
To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the same experimental pipelines developed fo...
-
Article
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
Myotonic dystrophy is a CUG repeat expansion disease and mice deficient in MBNL1, an RNA binding protein, show many characteristics of the disease. Comparison of gene expression profiles of two mouse models of...
-
Article
Understanding genome browsing
How can genome browsers help researchers to infer biological knowledge from data that might be misleading?
-
Article
Integration of biological networks and gene expression data using Cytoscape
Cytoscape is a free software package for visualizing, modeling and analyzing molecular and genetic interaction networks. This protocol explains how to use Cytoscape to analyze the results of mRNA expression pr...
