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Article
Open AccessGenome-wide characterisation of HD-Zip transcription factors and functional analysis of PbHB24 during stone cell formation in Chinese white pear (Pyrus bretschneideri)
The homodomain-leucine zipper (HD-Zip) is a conserved transcription factor family unique to plants that regulate multiple developmental processes including lignificaion. Stone cell content is a key determinant...
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Article
Hydrogen sulfide improves salt tolerance through persulfidation of PMA1 in Arabidopsis
A new interaction was found between PMA1 and GRF4. H2S promotes the interaction through persulfidated Cys446 of PMA1. H2S activates PMA1 to maintain K+/Na+ homeostasis through persulfidation under salt stress.
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Article
Characteristics of a novel temperate bacteriophage against Staphylococcus arlettae (vB_SarS_BM31)
Staphylococcus arlettae is a rarely reported coagulase-negative staphylococcus (CoNS) isolated from infected humans and livestock. Observing phage-bacteria interaction could improve the understanding of bacterial...
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Article
Open AccessChloroplast genome sequence of triploid Toxicodendron vernicifluum and comparative analyses with other lacquer chloroplast genomes
Toxicodendron vernicifluum, belonging to the family Anacardiaceae, is an important commercial arbor species, which can provide us with the raw lacquer, an excellent adhesive and painting material used to make lac...
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Article
Constitutive expression of two A-5 subgroup DREB transcription factors from desert shrub Ammopiptanthus mongolicus confers different stress tolerances in transgenic Arabidopsis
Dehydration-responsive element binding proteins (DREBs) constitute a large subfamily in the plant-specific APETALA2/ethylene-responsive factor (ERF) family and play crucial roles in plant stress tolerance. So ...
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Article
Open AccessSimultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis
Lipid homeostasis plays a fundamental role in the development of hepatocellular carcinoma (HCC). However, the mechanisms that regulate lipid homeostasis to avoid lipotoxicity in HCC remain elusive. Here, we fo...
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Article
The effects of deletion of cellobiohydrolase genes on carbon source-dependent growth and enzymatic lignocellulose hydrolysis in Trichoderma reesei
The saprophytic fungus Trichoderma reesei has long been used as a model to study microbial degradation of lignocellulosic biomass. The major cellulolytic enzymes of T. reesei are the cellobiohydrolases CBH1 and C...
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Article
Extension of C. elegans lifespan using the ·NO-delivery dinitrosyl iron complexes
The ubiquitous and emerging physiology function of endogenous nitric oxide in vascular, myocardial, immune, and neuronal systems prompts chemists to develop a prodrug for the controlled delivery of ·NO in vivo...
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Article
Open AccessOrchestration of H3K27 methylation: mechanisms and therapeutic implication
Histone proteins constitute the core component of the nucleosome, the basic unit of chromatin. Chemical modifications of histone proteins affect their interaction with genomic DNA, the accessibility of recogni...
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Article
Effects of average velocity on the growth and surface topography of biofilms attached to the reclaimed wastewater drip irrigation system laterals
Emitter clogging, a phenomenon commonly seen in reclaimed wastewater drip irrigation systems, is a severe obstacle to the wide applications and popularization of the irrigation technology. Some experiments sho...
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Article
Surface topographic characteristics of suspended particulates in reclaimed wastewater and effects on clogging in labyrinth drip irrigation emitters
Drip irrigation is the most effective and reliable method for reclaimed wastewater irrigation. Emitter clogging is the major problem for extending the drip irrigation technology. The existence of suspended par...
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Article
BRIT1/MCPH1 links chromatin remodelling to DNA damage response
Chromatin decondensation is required for repair factors to access damaged DNA. BRIT1/MCPH1, a damage response protein mutated in microcephaly, recruits the chromatin remodelling complex SWI/SNF to sites of DNA...