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    Article

    Population pharmacokinetic analysisof lamivudine, stavudine and zidovudine in controlled HIV-infected patients on HAART

    This work aimed at building a population pharmacokinetic (PK) model for lamivudine (LMV), stavudine (STV) and zidovudine (ZDV), estimating their inter and intraindividual PK variability and investigating the i...

    Xavière Panhard, Mayeule Legrand in European Journal of Clinical Pharmacology (2007)

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    Article

    High Variability of Indinavir and Nelfinavir Pharmacokinetics in HIV-infected Patients with a Sustained Virological Response on Highly Active Antiretroviral Therapy

    To describe plasma concentrations of indinavir alone or combined with ritonavir, and of nelfinavir and its active metabolite M8, and to measure their variabilities in HIV-infected patients treated with a stabl...

    Dr Cécile Goujard, Mayeule Legrand, Xavière Panhard in Clinical Pharmacokinetics (2005)

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    Article

    Pharmacodynamics and pharmacokinetics of single nasal (5 mg and 10 mg) and oral (50 mg) doses of ephedrine in healthy subjects

    Objective: To determine the cardiovascular, subjective effects and potential of abuse liability of single dose (–) ephedrine (E) administered orally (50 mg) or intranasally (10 mg and 5 mg). Methods: Sixteen hea...

    Ivan Berlin, Dominique Warot, Guy Aymard in European Journal of Clinical Pharmacology (2001)