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    Article

    RGB marking facilitates multicolor clonal cell tracking

    Kristoffer Weber et al. describe a new lentiviral vector-mediated RGB (red, green and blue) multicolor cell marking technique for analyzing clonal cell fates in vitro and in vivo. Here they use RGB marking to ass...

    Kristoffer Weber, Michael Thomaschewski, Michael Warlich, Tassilo Volz in Nature Medicine (2011)

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    Article

    Experimental models and therapeutic approaches for HBV

    Liver disease associated to persistent infection with the hepatitis B virus (HBV) continues to be a major health problem of global impact. In spite of the existence of an effective vaccine, approximately 360 m...

    Maura Dandri, Marc Lütgehetmann, Jörg Petersen in Seminars in Immunopathology (2013)

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    Article

    Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

    During cold stimulation, cholesterol is converted to bile acids in an alternative pathway. The bile acids then alter the microbiota, which in turn promotes more heat generation.

    Anna Worthmann, Clara John, Malte C Rühlemann, Miriam Baguhl in Nature Medicine (2017)

  4. Article

    Open Access

    Epigenetic modulation in chronic hepatitis B virus infection

    The human hepatitis B virus (HBV) is a small-enveloped DNA virus causing acute and chronic hepatitis. Despite the existence of an effective prophylactic vaccine and the strong capacity of approved antiviral dr...

    Maura Dandri in Seminars in Immunopathology (2020)

  5. Article

    Open Access

    Innate immunity in hepatitis B and D virus infection: consequences for viral persistence, inflammation, and T cell recognition

    Chronic infections with human hepatitis viruses continue to be a major health burden worldwide. Despite the availability of an effective prophylactic vaccine against the hepatitis B virus (HBV) and of antivira...

    Maura Dandri, Antonio Bertoletti, Marc Lütgehetmann in Seminars in Immunopathology (2021)