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Article
Open AccessThe skåne emergency medicine (SEM) cohort
In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2–3%. Better patient management decisions have the ...
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Article
Open AccessRetrospective validation study of an artificial neural network-based preoperative decision-support tool for noninvasive lymph node staging (NILS) in women with primary breast cancer (ISRCTN14341750)
Surgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However, SLNB may be associated with postoperative arm morbidities. For most pat...
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Chapter and Conference Paper
Understanding Survival Models Through Counterfactual Explanations
The development of black-box survival models has created a need for methods that explain their outputs, just as in the case of traditional machine learning methods. Survival models usually predict functions ra...
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Article
Open AccessMachine learning for early prediction of acute myocardial infarction or death in acute chest pain patients using electrocardiogram and blood tests at presentation
In the present study, we aimed to evaluate the performance of machine learning (ML) models for identification of acute myocardial infarction (AMI) or death within 30 days among emergency department (ED) chest ...
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Article
Open AccessThe implementation of a noninvasive lymph node staging (NILS) preoperative prediction model is cost effective in primary breast cancer
The need for sentinel lymph node biopsy (SLNB) in clinically node-negative (cN0) patients is currently questioned. Our objective was to investigate the cost-effectiveness of a preoperative noninvasive lymph no...
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Article
Open AccessDeterministic annealing with Potts neurons for multi-robot routing
A deterministic annealing (DA) method is presented for solving the multi-robot routing problem with min–max objective. This is an NP-hard problem belonging to the multi-robot task allocation set of problems wh...
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Article
Open AccessArtificial neural network models to predict nodal status in clinically node-negative breast cancer
Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nod...
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Article
Open AccessCorrection to: 3D skeletal uptake of 18F sodium fluoride in PET/CT images is associated with overall survival in patients with prostate cancer
Following publication of the original article [1], the authors flagged the that the Kaplan-Meier curve in Fig. 6 is a duplication of the Kaplan-Meier curve in Fig. 5, which is not correct.
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Article
Open AccessImproving prediction of heart transplantation outcome using deep learning techniques
The primary objective of this study is to compare the accuracy of two risk models, International Heart Transplantation Survival Algorithm (IHTSA), developed using deep learning technique, and Index for Mortali...
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Article
Open Access3D skeletal uptake of 18F sodium fluoride in PET/CT images is associated with overall survival in patients with prostate cancer
Sodium fluoride (NaF) positron emission tomography combined with computer tomography (PET/CT) has shown to be more sensitive than the whole-body bone scan in the detection of skeletal uptake due to metastases ...
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Article
Open AccessStatistical power considerations in genotype-based recall randomized controlled trials
Randomized controlled trials (RCT) are often underpowered for validating gene-treatment interactions. Using published data from the Diabetes Prevention Program (DPP), we examined power in conventional and genotyp...
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Article
Open AccessAbility of emergency physicians to diagnose acute coronary syndrome on the ECG of acute chest pain patients
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Article
Open AccessBone Scan Index as a prognostic imaging biomarker during androgen deprivation therapy
Bone Scan Index (BSI) is a quantitative measurement of tumour burden in the skeleton calculated from bone scan images. When analysed at the time of diagnosis,it has been shown to provide prognostic information...
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Article
Open AccessAnalysis of regional bone scan index measurements for the survival of patients with prostate cancer
A bone scan is a common method for monitoring bone metastases in patients with advanced prostate cancer. The Bone Scan Index (BSI) measures the tumor burden on the skeleton, expressed as a percentage of the to...
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Article
Open AccessProgression of bone metastases in patients with prostate cancer - automated detection of new lesions and calculation of bone scan index
The objective of this study was firstly to develop and evaluate an automated method for the detection of new lesions and changes in bone scan index (BSI) in serial bone scans and secondly to evaluate the progn...
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Article
Open AccessPrognosis of patients without perfusion defects with and without rest study in myocardial perfusion scintigraphy
Stress myocardial perfusion scintigraphy (MPS) is widely regarded as a useful imaging modality for diagnosing patients with suspected ischemic heart disease. Current European guidelines recommend stress study ...
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Article
Open AccessCODUSA - Customize Optimal Donor Using Simulated Annealing In Heart Transplantation
In heart transplantation, selection of an optimal recipient-donor match has been constrained by the lack of individualized prediction models. Here we developed a customized donor-matching model (CODUSA) for pa...
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Article
Open AccessBone Scan Index: a prognostic imaging biomarker for high-risk prostate cancer patients receiving primary hormonal therapy
The objective of this study was to explore the prognostic value of the Bone Scan Index (BSI) obtained at the time of diagnosis in a group of high-risk prostate cancer patients receiving primary hormonal therapy.
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Article
Open AccessLikelihood of acute coronary syndrome in emergency department chest pain patients varies with time of presentation
There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest...
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Article
Open AccessReferring physicians underestimate the extent of abnormalities in final reports from myocardial perfusion imaging
It is important that referring physicians and other treating clinicians properly understand the final reports from diagnostic tests. The aim of the study was to investigate whether referring physicians interpr...
