8 Result(s)

Article

Author Correction: Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Yun Shan Goh, Siew-Wai Fong, Matthew Zirui Tay, Angeline Rouers… in Scientific Reports (2024)

Article

Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta wave

Identification of the risk factors and the high-risk groups which are most vulnerable is critical in COVID-19 disease management at a population level. Evaluating the efficacy of vaccination against infections...

Yun Shan Goh, Siew-Wai Fong, Matthew Zirui Tay, Angeline Rouers… in Scientific Reports (2023)

Article

Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

Understanding the impact of age on vaccinations is essential for the design and delivery of vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of multiple compartments of the ...

Laurent Renia, Yun Shan Goh, Angeline Rouers, Nina Le Bert… in Nature Communications (2022)

Article

Correction to: Robust Virus‐Specific Adaptive Immunity in COVID‐19 Patients with SARS‐CoV‐2 Δ382 Variant Infection

Siew‐Wai Fong, Nicholas Kim‐Wah Yeo, Yi‐Hao Chan… in Journal of Clinical Immunology (2022)

Article

Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that have become dominant as the pandemic progresses bear the ORF8 mutation together with multiple spike mutations. A...

Siew-Wai Fong, Nicholas Kim-Wah Yeo, Yi-Hao Chan… in Journal of Clinical Immunology (2022)

Article

Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells

More than one-third of the world’s population is exposed to Plasmodium vivax malaria, mainly in Asia¹. P. vivax preferentially invades reticulocytes (immature red blood cells)^2–4. Previous work has identified 11 ...

Benoît Malleret, Abbas El Sahili, Matthew Zirui Tay… in Nature Microbiology (2021)

Article

The trinity of COVID-19: immunity, inflammation and intervention

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into the virology of SARS-CoV-2, unders...

Matthew Zirui Tay, Chek Meng Poh, Laurent Rénia… in Nature Reviews Immunology (2020)

Article

Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

Distinct regions of long-range genetic fixation in the human MHC region, known as conserved extended haplotypes (CEHs), possess unique genomic characteristics and are strongly associated with numerous diseases...

Tze Hau Lam, Matthew Zirui Tay, Bei Wang, Ziwei **ao, Ee Chee Ren in Scientific Reports (2015)