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Article
Open AccessA Drosophila model relevant to chemotherapy-related cognitive impairment
Chemotherapy-related cognitive impairment (CRCI) is a common adverse effect of treatment and is characterized by deficits involving multiple cognitive domains including memory. Despite the significant morbidit...
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Article
Open AccessAromatized liposomes for sustained drug delivery
Insufficient drug loading and leakage of payload remain major challenges in designing liposome-based drug delivery systems. These phenomena can limit duration of effect and cause toxicity. Targeting the rate-l...
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Article
Revisiting a Telencephalic Extent of the Ascending Reticular Activating System
Is the cerebrum involved in its own activation to states of attention or arousal? “Telencephalon” is a term borrowed from embryology to identify not only the cerebral hemispheres of the forebrain, but also the...
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Article
Open AccessAn aptamer-based depot system for sustained release of small molecule therapeutics
Delivery of hydrophilic small molecule therapeutics by traditional drug delivery systems is challenging. Herein, we have used the specific interaction between DNA aptamers and drugs to create simple and effect...
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Article
The epidemiology of primary and metastatic brain tumors in infancy through childhood
To evaluate the epidemiology of primary and metastatic pediatric brain tumors in the United States according to the WHO CNS 4th and 5th editions classifications.
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Perioperative Management of Sleep Apnea Patients in an Ambulatory Surgical Setting
Sleep apnea is a disorder affecting 25–30 million Americans, with significantly more remaining undiagnosed. In fact, it is estimated that 80% of moderate to severe OSA cases are undiagnosed. These patients are...
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Article
Open AccessMolecular and clinicopathologic features of gliomas harboring NTRK fusions
Fusions involving neurotrophic tyrosine receptor kinase (NTRK) genes are detected in ≤2% of gliomas and can promote gliomagenesis. The remarkable therapeutic efficacy of TRK inhibitors, which are among the first ...
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Chapter
Cerebrospinal Fluid
Cytologic examination of cerebrospinal fluid (CSF) plays an integral role in the evaluation and prognosis of myriad conditions involving the central nervous system, including malignancy and infection. In this ...
