4 Result(s)

Article

Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways

Globally decreased histone 3, lysine 27 tri-methylation (H3K27me3) is a hallmark of H3K27-altered diffuse midline gliomas (DMGs) and group-A posterior fossa ependymomas (PFAs). H3K27-altered DMGs are largely c...

Matthew Pun, Drew Pratt, Patricia R. Nano… in Acta Neuropathologica Communications (2023)

Article

H3K27M-mutant diffuse midline glioma with extensive intratumoral microthrombi in a young adult with COVID-19-associated coagulopathy

Matthew Pun, James Haggerty-Skeans, Drew Pratt, Yelena Fudym… in Acta Neuropathologica (2020)

Article

Unraveling the clinicopathological features driving the emergence of ESR1 mutations in metastatic breast cancer

ESR1 mutations were recently found to be an important mechanism of endocrine resistance in ER-positive (ER + ) metastatic breast cancer. To determine the clinicopathological features driving the emergence of the

Yanan Kuang, Bilal Siddiqui, Jiani Hu, Matthew Pun, MacIntosh Cornwell… in npj Breast Cancer (2018)

Article

VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis

RNA sequencing has become a ubiquitous technology used throughout life sciences as an effective method of measuring RNA abundance quantitatively in tissues and cells. The increase in use of RNA-seq technology ...

MacIntosh Cornwell, Mahesh Vangala, Len Taing, Zachary Herbert… in BMC Bioinformatics (2018)