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  1. No Access

    Protocol

    Real-Time PCR Assay for the Analysis of Alternative Splicing of Immune Mediators in Cancer

    Alternative splicing evolved as a very efficient way to generate proteome diversity and to regulate cell homeostasis from a limited number of genes. Moreover, changes in the relative amounts of different splic...

    Ruizhi Wang, Md. Faruk Hossain, Jovan Mirkovic… in Immune Mediators in Cancer (2020)

  2. No Access

    Protocol

    Radiolabeled Semi-quantitative RT-PCR Assay for the Analysis of Alternative Splicing of Interleukin Genes

    Alternative splicing evolved as a very efficient way to generate proteome diversity from a limited number of genes, while at the same time modulating posttranscriptional events of gene expression—such as stabi...

    Felitsiya Shakola, Stephen Byrne, Kainaat Javed, Matteo Ruggiu in Cytokine Bioassays (2014)

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    Article

    Nova regulates brain-specific splicing to shape the synapse

    Alternative RNA splicing greatly increases proteome diversity and may thereby contribute to tissue-specific functions. We carried out genome-wide quantitative analysis of alternative splicing using a custom Af...

    Jernej Ule, Aljaž Ule, Joanna Spencer, Alan Williams, **g-Shan Hu… in Nature Genetics (2005)