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Article
Open AccessPredictors of coronary artery injury after orbital atherectomy as assessed by optical coherence tomography
Purpose: The association between the extent of the wire and device bias as assessed by optical coherence tomography (OCT) in the healthy portion of the vessel and the risk of coronary artery injury after orbital ...
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Article
Open AccessExperience-dependent changes in affective valence of taste in male mice
Taste plays an essential role in the evaluation of food quality by detecting potential harm and benefit in what animals are about to eat and drink. While the affective valence of taste signals is supposed to b...
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Article
Open AccessParabrachial-to-parasubthalamic nucleus pathway mediates fear-induced suppression of feeding in male mice
Feeding behavior is adaptively regulated by external and internal environment, such that feeding is suppressed when animals experience pain, sickness, or fear. While the lateral parabrachial nucleus (lPB) play...
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Article
Open AccessThe parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice
The neuronal circuitry for pain signals has been intensively studied for decades. The external lateral parabrachial nucleus (PB) was shown to play a crucial role in nociceptive information processing. Previous...
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Article
Open AccessAn engineered channelrhodopsin optimized for axon terminal activation and circuit map**
Optogenetic tools such as channelrhodopsin-2 (ChR2) enable the manipulation and map** of neural circuits. However, ChR2 variants selectively transported down a neuron’s long-range axonal projections for prec...
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Article
Open AccessPathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes
Pogo transposable element derived with ZNF domain (POGZ) has been identified as one of the most recurrently de novo mutated genes in patients with neurodevelopmental disorders (NDDs), including autism spectrum di...
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Article
Open AccessCellular tagging as a neural network mechanism for behavioural tagging
Behavioural tagging is the transformation of a short-term memory, induced by a weak experience, into a long-term memory (LTM) due to the temporal association with a novel experience. The mechanism by which neu...
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Article
Open AccessThe lateral parabrachial nucleus is actively involved in the acquisition of fear memory in mice
Pavlovian fear conditioning is a form of learning accomplished by associating a conditioned stimulus (CS) and an unconditioned stimulus (US). While CS–US associations are generally thought to occur in the amyg...
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Article
Open AccessSynaptic potentiation in the nociceptive amygdala following fear learning in mice
Pavlovian fear conditioning is a classical form of associative learning, which depends on associative synaptic plasticity in the amygdala. Recent findings suggest that the central amygdala (CeA) plays an activ...
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Article
Open AccessRole of capsaicin-sensitive C-fiber afferents in neuropathic pain-induced synaptic potentiation in the nociceptive amygdala
Neurons in the capsular part of the central nucleus of the amygdala (CeC), a region also called "nociceptive amygdala," receive nociceptive information from the dorsal horn via afferent pathways relayed from t...
