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  1. No Access

    Article

    Survival outcomes of patients with stage III colorectal cancer aged ≥ 80 years who underwent curative resection: the HiSCO-04 prospective cohort study

    The efficacy of adjuvant chemotherapy in elderly patients aged ≥ 80 years with stage III colorectal cancer remains unclear. In parallel with a multicenter prospective phase II trial evaluating the efficacy of ...

    Tetsuya Mochizuki, Manabu Shimomura in International Journal of Clinical Oncology (2024)

  2. No Access

    Article

    Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub-analysis of the HiSCO-04 study

    Adjuvant chemotherapy is recommended following colorectal cancer resection based on risk of recurrence. In older patients, treatment decisions should consider recurrence rates and tolerability, as well as func...

    Tomoaki Bekki, Manabu Shimomura in International Journal of Colorectal Disease (2023)

  3. No Access

    Article

    Predictive factors associated with anastomotic leakage after resection of rectal cancer: a multicenter study with the Hiroshima Surgical study group of Clinical Oncology

    Several factors have been reported as risk factors for anastomotic leakage after resection of rectal cancer. This study aimed to evaluate the risk factors for anastomotic leakage, including nutritional and imm...

    Tomoaki Bekki, Manabu Shimomura, Tomohiro Adachi in Langenbeck's Archives of Surgery (2023)

  4. No Access

    Article

    A prospective feasibility study of uracil–tegafur and leucovorin as adjuvant chemotherapy for patients aged ≥ 80 years after curative resection of colorectal cancer, the HiSCO-03 study

    There is no consensus on the safety and effectiveness of adjuvant chemotherapy for patients with stage III colorectal cancer (CRC) aged ≥ 80 years. We conducted a prospective multi-institutional phase II study...

    Hiroshi Okuda, Manabu Shimomura, Satoshi Ikeda in Cancer Chemotherapy and Pharmacology (2023)

  5. Article

    Open Access

    Giant esophageal liposarcoma with squamous cell carcinoma resected via the cervical approach: a case report

    Liposarcoma is one of the most common soft tissue sarcomas, but is extremely rarely found in the esophagus. There have been no reports of esophageal liposarcoma together with superficial carcinoma of the esoph...

    Tomohiro Okura, Yasuhiro Shirakawa, Yuki Katsura, Takuya Yano in Surgical Case Reports (2022)

  6. Article

    Open Access

    Cutaneous metastasis of cecum cancer with MSI-high and BRAFV600E mutation: a case report

    Cutaneous metastases of colorectal cancer (CRC) are rare, occurring in 0.7% to 5% of cancer patients. Furthermore, the molecular subtypes of cutaneous metastasis of CRC are unclear. Here, we present a rare cas...

    Kosuke Yunoki, Takuya Yano, Masanori Yoshimitsu, Ko Oshita in Surgical Case Reports (2021)

  7. No Access

    Article

    Prognostic value of preoperative carcinoembryonic antigen and D-dimer concentrations in patients undergoing curative resection for colorectal cancer

    Carcinoembryonic antigen (CEA) has limited value as a standalone predictor of the survival in patients with colorectal cancer (CRC). D-dimer (DD) is a predictor of the survival in patients with metastatic CRC....

    Yasutomo Ojima, Masao Harano, Daisuke Sumitani, Masanori Yoshimitsu in Surgery Today (2021)

  8. No Access

    Article

    Indocyanine green fluorescence imaging for subtotal esophagectomy due to esophageal stenosis after acute esophageal necrosis: a report of two cases

    Although esophageal stricture after acute esophageal necrosis (AEN) is often refractory to dilation therapy, there have been few reports of surgical intervention. We report two rare cases of successful subtota...

    Kouki Imaoka, Masao Harano, Ko Oshita, Takuya Yano in Clinical Journal of Gastroenterology (2021)

  9. No Access

    Article

    Acute cholecystitis caused by gallbladder metastasis from non-small cell lung cancer: a case report

    Although non-small cell lung cancer can metastasize to any part of the body, metastasis to the gallbladder is extremely rare. We present a case of acute cholecystitis caused by gallbladder metastasis from non-...

    Kouki Imaoka, Daisuke Satoh, Ko Oshita, Takuya Yano in Clinical Journal of Gastroenterology (2021)

  10. Article

    Open Access

    Gluteal-fold flap repair of rectovaginal fistula caused by aluminum potassium sulfate hydrate-tannic acid injection for internal hemorrhoids: a case report

    Rectovaginal fistula (RVF) following aluminum potassium sulfate hydrate-tannic acid (ALTA) injection therapy for hemorrhoids is a rare complication. We report the first case of RVF after ALTA injection therapy...

    Masanori Yoshimitsu, Hiroyuki Egi, Shogo Nagamatsu in Surgical Case Reports (2020)

  11. No Access

    Article

    Short-term outcomes of laparoscopic surgery in octogenarians with colorectal cancer: a single-institution analysis

    The number of elderly patients with colorectal cancer (CRC) treated with surgery has gradually increased. The aim of this study was to evaluate the short-term outcomes in patients ≥80 years of age who underwen...

    Masashi Miguchi, Masanori Yoshimitsu, Keishi Hakoda, Ichiro Omori in Surgery Today (2018)

  12. Article

    Open Access

    A multi-institutional feasibility study of S-1/oxaliplatin plus bevacizumab in patients with advanced/metastatic colorectal cancer: the HiSCO-02 prospective phase II study

    FOLFOX is a standard combination chemotherapy regimen for metastatic colorectal cancer (CRC). 5-Fluorouracil (5-FU) is infused continuously through a pump for 46 h; therefore, replacement of infused 5-FU with ...

    Manabu Shimomura, Katsunori Shinozaki, Takao Hinoi, Masanori Yoshimitsu in SpringerPlus (2016)

  13. No Access

    Article

    A case of thoracic esophageal cancer with an unusual type of duplicated inferior vena cava

    We describe here a thoracic esophageal cancer with an unusual type of duplicated inferior vena cava. A 58-year-old man was referred to our hospital because a tumor in his lower esophagus had been identified by...

    Ryuta Shintakuya, Hidenori Mukaida in General Thoracic and Cardiovascular Surgery (2014)

  14. No Access

    Article

    Inguinal hernia repair with the mesh plug method is safe after radical retropubic prostatectomy

    We evaluated the safety and efficiency of using the mesh plug method (MP) to repair inguinal hernias in patients with a history of radical retropubic prostatectomy (RRP). We also investigated how RRP influenc...

    Hiroaki Niitsu, Junya Taomoto, Koji Mita, Masanori Yoshimitsu in Surgery Today (2014)

  15. No Access

    Chapter

    Technical Considerations

    In this paper we describe the basic techniques for a single-port laparoscopic surgery. The surgical techniques are classified into the multiple trocar method and the multi-channel port method because of access...

    Masazumi Okajima, Yasutomo Ojima, Masanori Yoshimitsu in Reduced Port Laparoscopic Surgery (2014)

  16. Article

    Open Access

    Using the Objective Structured Assessment of Technical Skills (OSATS) global rating scale to evaluate the skills of surgical trainees in the operating room

    The education of surgical trainees should be based on an accurate evaluation of their surgical skill levels. In our hospital, the Objective Structured Assessment of Technical Skills (OSATS) is used for this pu...

    Hiroaki Niitsu, Naoki Hirabayashi, Masanori Yoshimitsu, Takeshi Mimura in Surgery Today (2013)

  17. No Access

    Article

    Alterations in portal vein blood pH, hepatic functions, and hepatic histology in a porcine carbon dioxide pneumoperitoneum model

    Intra-abdominal high pressure and acidosis by carbon dioxide (CO2) pneumoperitoneum is known to affect various organ functions. In this study, changes in liver functions and liver histology were investigated duri...

    Makoto Yoshida, Satoshi Ikeda, Daisuke Sumitani, Yuji Takakura in Surgical Endoscopy (2010)

  18. No Access

    Article

    Gastrointestinal stromal tumors of the small intestine in pediatric populations: a case report and literature review

    An 18-year-old girl presented with abdominal pain and a tumor was subsequently detected in the jejunum. We therefore carried out a wedge resection of the jejunum. The diagnosis of GIST was confirmed histologic...

    Manabu Shimomura, Satoshi Ikeda, Yuji Takakura in Pediatric Surgery International (2010)

  19. No Access

    Article

    Hybrid Hand-Assisted Colectomy for Transverse Colon Cancer: A Useful Technique for Non-Expert Laparoscopic Surgeons

    Laparoscopic assisted colectomy (LAC) is commonly performed, but LAC for transverse colon cancer is a complex procedure, even in the hands of experts. In particular, laparoscopic take-down of the splenic and/o...

    Yuji Takakura, Masazumi Okajima, Masanori Yoshimitsu in World Journal of Surgery (2009)

  20. Article

    Open Access

    Retroperitoneal abscess complicated with necrotizing fasciitis of the thigh in a patient with sigmoid colon cancer

    Necrotizing fasciitis of the thigh due to the colon cancer, especially during chemotherepy, has not been previously reported.

    Yuji Takakura, Satoshi Ikeda, Masanori Yoshimitsu in World Journal of Surgical Oncology (2009)

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