3 Result(s)
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Masahiro Sugiura
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessThe heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
The 4F2 cell-surface antigen heavy chain (4F2hc) forms a heterodimeric complex with L-type amino acid transporter 1 (LAT1) and transports large neutral essential amino acids. However, in contrast to the tradit...
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Article
Open AccessStructural insights into the mechanism of rhodopsin phosphodiesterase
Rhodopsin phosphodiesterase (Rh-PDE) is an enzyme rhodopsin belonging to a recently discovered class of microbial rhodopsins with light-dependent enzymatic activity. Rh-PDE consists of the N-terminal rhodopsin...
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Article
Open AccessExpression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma
L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional r...
