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  1. Article

    Open Access

    Ultra Rapid Lispro (URLi) Accelerates Insulin Lispro Absorption and Insulin Action vs Humalog® Consistently Across Study Populations: A Pooled Analysis of Pharmacokinetic and Glucodynamic Data

    Ultra rapid lispro (URLi) is a novel insulin lispro formulation developed to more closely match physiological insulin secretion and improve postprandial glucose control. This pooled analysis compared the pharm...

    Jennifer Leohr, Mary Anne Dellva, Kallin Carter in Clinical Pharmacokinetics (2021)

  2. Article

    Open Access

    Long-Term Efficacy and Safety of Ultra Rapid Lispro (URLi) in Adults with Type 1 Diabetes: The PRONTO-T1D Extension

    The PRONTO-T1D study, which evaluated the efficacy and safety of ultra rapid lispro (URLi) versus lispro in adults with type 1 diabetes (T1D), met the primary endpoint of noninferiority of HbA1c change from ba...

    Juliana Bue-Valleskey, Leslie Klaff, Jang Ik Cho, Mary Anne Dellva in Diabetes Therapy (2021)

  3. Article

    Open Access

    Pharmacokinetics and Glucodynamics of Ultra Rapid Lispro (URLi) versus Humalog® (Lispro) in Patients with Type 2 Diabetes Mellitus: A Phase I Randomised, Crossover Study

    Ultra rapid lispro (URLi) is a novel insulin lispro formulation developed to more closely match physiological insulin secretion and improve postprandial glucose control. This study compared the insulin lispro ...

    Jennifer Leohr, Mary Anne Dellva, David E. Coutant in Clinical Pharmacokinetics (2020)

  4. Article

    Open Access

    Pharmacokinetics and Glucodynamics of Ultra Rapid Lispro (URLi) versus Humalog® (Lispro) in Younger Adults and Elderly Patients with Type 1 Diabetes Mellitus: A Randomised Controlled Trial

    Ultra rapid lispro (URLi) is a novel insulin lispro formulation developed to more closely match physiological insulin secretion and improve postprandial glucose control. This study compared the pharmacokinetic...

    Helle Linnebjerg, Qianyi Zhang, Elizabeth LaBell in Clinical Pharmacokinetics (2020)

  5. Article

    Open Access

    Bioequivalence of Ultra Rapid Lispro (URLi) U100 and U200 Formulations in Healthy Subjects

    Ultra rapid lispro (URLi) is a novel insulin lispro formulation that was developed to more closely match physiological insulin secretion. The aims of this study were to demonstrate the bioequivalence (BE) of a...

    Helle Linnebjerg, Elizabeth Smith LaBell, Mary Anne Dellva in Diabetes Therapy (2020)