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  1. Article

    Open Access

    The pancancer overexpressed NFYC Antisense 1 controls cell cycle mitotic progression through in cis and in trans modes of action

    Antisense RNAs (asRNAs) represent an underappreciated yet crucial layer of gene expression regulation. Generally thought to modulate their sense genes in cis through sequence complementarity or their act of trans...

    Cecilia Pandini, Giulia Pagani, Martina Tassinari, Emanuele Vitale… in Cell Death & Disease (2024)

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  2. No Access

    Article

    Unyvero ITI® system for the clinical resolution of discrepancies in periprosthetic joint infection diagnosis

    The Unyvero molecular assay was tested for the clinical resolution of discordant results, evaluating its role in prosthetic joint infection diagnosis.

    Silvia Zannoli, Andrea Sambri, Manuela Morotti… in MUSCULOSKELETAL SURGERY (2021)

  3. Article

    Open Access

    The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes

    G-quadruplexes are four-stranded conformations of nucleic acids that act as cellular epigenetic regulators. A dynamic G-quadruplex forming region in the HIV-1 LTR promoter represses HIV-1 transcription when in...

    Matteo Scalabrin, Ilaria Frasson, Emanuela Ruggiero, Rosalba Perrone… in Scientific Reports (2017)

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    Article

    Mitotane enhances doxorubicin cytotoxic activity by inhibiting P-gp in human adrenocortical carcinoma cells

    Mitotane is currently employed as adjuvant therapy as well as in the medical treatment of adrenocortical carcinoma (ACC), alone or in combination with chemotherapeutic agents. It was previously demonstrated th...

    Teresa Gagliano, Erica Gentilin, Katiuscia Benfini, Carmelina Di Pasquale… in Endocrine (2014)