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  1. Article

    Open Access

    Guidance of adjuvant instillation in intermediate-risk non-muscle invasive bladder cancer by drug screens in patient derived organoids: a single center, open-label, phase II trial

    In intermediate-risk non-muscle invasive bladder cancer (NMIBC) clinical guidelines suggest an adjuvant instillation with a chemotherapeutic agent. However, the agent and regimen are not clearly defined. World...

    Roland Seiler, Martin Egger, Marta De Menna, Saskia Wehrli, Martina Minoli in BMC Urology (2023)

  2. Article

    Open Access

    Bladder cancer organoids as a functional system to model different disease stages and therapy response

    Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs)...

    Martina Minoli, Thomas Cantore, Daniel Hanhart, Mirjam Kiener in Nature Communications (2023)

  3. Article

    Open Access

    Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification

    Little is known about the relationship between the metabolite profile of plasma from pre-operative prostate cancer (PCa) patients and the risk of PCa progression. In this study we investigated the association ...

    Eugenio Zoni, Martina Minoli, Cédric Bovet, Anne Wehrhan in BMC Cancer (2019)