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Article
Proteome survey reveals modularity of the yeast cell machinery
Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. Here we report the first genome-wide screen for complexes in an organism, budding yeast, using ...
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Article
Functional organization of the yeast proteome by systematic analysis of protein complexes
Most cellular processes are carried out by multiprotein complexes. The identification and analysis of their components provides insight into how the ensemble of expressed proteins (proteome) is organized into ...