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  1. No Access

    Article

    Utility of C57BL/6J × 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to γ radiation and microsatellite polymorphism

    We have previously reported a method for making nested deletion complexes in mice by irradiation of ES cells. The key to this technology is that F1 hybrid ES cells (called v17.2) of the genotype (BALB/cTa × 129/S...

    Yun You, Rebecca Bersgtram, Martina Klemm, Heather Nelson… in Mammalian Genome (1998)

  2. No Access

    Article

    Chromosomal deletion complexes in mice by radiation of embryonic stem cells

    Chromosomal deletions (‘deficiencies’) are powerful tools in the genetic analysis of complex genomes. They have been exploited extensively in Drosophila melanogaster, an organism in which deficiencies can be effi...

    Yun You, Rebecca Bergstrom, Martina Klemm, Birgit Lederman… in Nature Genetics (1997)