-
Article
Open AccessHigh-throughput electron tomography identifies centriole over-elongation as an early event in plasma cell disorders
Plasma cell disorders are clonal outgrowths of pre-malignant or malignant plasma cells, characterized by extensive chromosomal aberrations. Centrosome abnormalities are a major driver of chromosomal instabilit...
-
Article
Open AccessMicrotubule depolymerization contributes to spontaneous neurotransmitter release in vitro
Microtubules are key to multiple neuronal functions involving the transport of organelles, however, their relationship to neurotransmitter release is still unresolved. Here, we show that microtubules present i...
-
Article
MoBIE: a Fiji plugin for sharing and exploration of multi-modal cloud-hosted big image data
-
Chapter
Resolving the Process of Clathrin Mediated Endocytosis Using Correlative Light and Electron Microscopy (CLEM)
This chapter will present the computational approach of registering images from different modalities based on manual selection of matching pairs of landmarks. Here we will present an image registration workflo...
-
Article
Software tools for automated transmission electron microscopy
The demand for high-throughput data collection in electron microscopy is increasing for applications in structural and cellular biology. Here we present a combination of software tools that enable automated ac...
-
Article
Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings
The nuclear envelope has to be reformed after mitosis to create viable daughter cells with closed nuclei. How membrane sealing of DNA and assembly of nuclear pore complexes (NPCs) are achieved and coordinated ...
