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    Article

    Endothelial BMP4 Promotes Leukocyte Rolling and Adhesion and Is Elevated in Patients After Survived Out-of-Hospital Cardiac Arrest

    Leukocyte recruitment is a fundamental step in the inflammatory response during ischemia/reperfusion injury (IRI). Rolling and adhesion of leukocytes to activated endothelium promote tissue inflammation after ...

    Linus Arnold, Miki Weberbauer, Marius Herkel, Katrin Fink, Hans-Jörg Busch… in Inflammation (2020)

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    Article

    Semaphorin 3F Promotes Transendothelial Migration of Leukocytes in the Inflammatory Response After Survived Cardiac Arrest

    Leukocyte transmigration through the blood vessel wall is a fundamental step of the inflammatory response and requires expression of adhesion molecule PECAM-1. Accumulating evidence implicates that semaphorin ...

    Stephanie Reichert, Stefanie Scheid, Tina Roth, Marius Herkel… in Inflammation (2019)

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    Article

    Endothelial BMP4 Regulates Leukocyte Diapedesis and Promotes Inflammation

    Leukocyte recruitment is a fundamental event in the response of the innate immune system to injury. This process is promoted in part by the opening of endothelial cell adherens junctions that allows leukocyte ...

    Thomas Helbing, Linus Arnold, Gwendoline Wiltgen, Eva Hirschbihl… in Inflammation (2017)

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    Article

    Bone Morphogenetic Protein-Modulator BMPER Regulates Endothelial Barrier Function

    The endothelium serves as a selective barrier and controls the exchange of nutrients, hormones, and leukocytes between blood and tissues. Molecular mechanisms contributing to the pathogenesis of endothelial ba...

    Thomas Helbing, Gwendoline Wiltgen, Alexandra Hornstein, Elena Z. Brauers… in Inflammation (2017)

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    Chapter

    The Role of Thrombin in Vascular Development

    Vasculogenesis is essential for embryonic development. The vasculature and the intravascular blood compartment develop in a close spatial and temporal relationship. Here we discuss how thrombin, as the common ...

    Martin Moser, Cam Patterson* in Thrombin (2009)