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  1. No Access

    Article

    Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

    A growing number of studies have examined alterations in white matter organization in people with posttraumatic stress disorder (PTSD) using diffusion MRI (dMRI), but the results have been mixed which may be p...

    Emily L. Dennis, Seth G. Disner, Negar Fani, Lauren E. Salminen in Molecular Psychiatry (2021)

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    Article

    White matter abnormalities across the lifespan of schizophrenia: a harmonized multi-site diffusion MRI study

    Several prominent theories of schizophrenia suggest that structural white matter pathologies may follow a developmental, maturational, and/or degenerative process. However, a lack of lifespan studies has precl...

    Suheyla Cetin-Karayumak, Maria A. Di Biase, Natalia Chunga in Molecular Psychiatry (2020)

  3. No Access

    Chapter and Conference Paper

    Pairwise, Ordinal Outlier Detection of Traumatic Brain Injuries

    Because mild Traumatic Brain Injuries (mTBI) are heterogeneous, classification methods perform outlier detection from a model of healthy tissue. Such a model is challenging to construct. Instead, we utilize re...

    Matt Higger, Martha Shenton, Sylvain Bouix in Brainlesion: Glioma, Multiple Sclerosis, S… (2018)

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    Article

    The white matter query language: a novel approach for describing human white matter anatomy

    We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volum...

    Demian Wassermann, Nikos Makris, Yogesh Rathi in Brain Structure and Function (2016)

  5. No Access

    Article

    Multi-tensor investigation of orbitofrontal cortex tracts affected in subcaudate tractotomy

    Subcaudate tractotomy (SCT) is a neurosurgical lesioning procedure that can reduce symptoms in medically intractable obsessive compulsive disorder (OCD). Due to the putative importance of the orbitofrontal cor...

    Jimmy C. Yang, George Papadimitriou, Ryan Eckbo in Brain Imaging and Behavior (2015)

  6. No Access

    Article

    Abnormalities in Myelination of the Superior Cerebellar Peduncle in Patients with Schizophrenia and Deficits in Movement Sequencing

    Deficits in the execution of a sequence of movements are common in schizophrenia. Previous studies reported reduced functional activity in the motor cortex and cerebellum in schizophrenic patients with deficit...

    Jitka Hüttlova, Zora Kikinis, Milos Kerkovsky, Sylvain Bouix, Mai-Anh Vu in The Cerebellum (2014)

  7. Chapter and Conference Paper

    On Describing Human White Matter Anatomy: The White Matter Query Language

    The main contribution of this work is the careful syntactical definition of major white matter tracts in the human brain based on a neuroanatomist’s expert knowledge. We present a technique to formally describ...

    Demian Wassermann, Nikos Makris in Medical Image Computing and Computer-Assis… (2013)

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    Chapter and Conference Paper

    White Matter Bundle Registration and Population Analysis Based on Gaussian Processes

    This paper proposes a method for the registration of white matter tract bundles traced from diffusion images and its extension to atlas generation. Our framework is based on a Gaussian process representation o...

    Demian Wassermann, Yogesh Rathi, Sylvain Bouix in Information Processing in Medical Imaging (2011)

  9. No Access

    Chapter and Conference Paper

    Shape Modeling and Analysis with Entropy-Based Particle Systems

    This paper presents a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization. The method requires very lit...

    Joshua Cates, P. Thomas Fletcher in Information Processing in Medical Imaging (2007)

  10. Chapter and Conference Paper

    Logarithm Odds Maps for Shape Representation

    The concept of the Logarithm of the Odds (LogOdds) is frequently used in areas such as artificial neural networks, economics, and biology. Here, we utilize LogOdds for a shape representation that demonstrates ...

    Kilian M. Pohl, John Fisher, Martha Shenton in Medical Image Computing and Computer-Assis… (2006)

  11. Chapter and Conference Paper

    Discriminative MR Image Feature Analysis for Automatic Schizophrenia and Alzheimer’s Disease Classification

    We construct a computational framework for automatic central nervous system (CNS) disease discrimination using high resolution Magnetic Resonance Images (MRI) of human brains. More than 3000 MR image features ...

    Yanxi Liu, Leonid Teverovskiy in Medical Image Computing and Computer-Assis… (2004)

  12. No Access

    Chapter and Conference Paper

    Automating segmentation of dual-echo MR head data

    Multiecho MR acquisition yields various information about tissue and csf characteristics. The analysis of two-dimensional scatterplots generated from dual-echo MR data turns out to be a useful tool. It allows ...

    Guido Gerig, John Martin, Ron Kikinis in Information Processing in Medical Imaging (1991)