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  1. No Access

    Article

    The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte–Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity

    Considerable efforts are currently made to develop strategies that boost endogenous recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic factors are attractive candidates th...

    Ahmet Burak Caglayan, Mustafa Caglar Beker… in Translational Stroke Research (2023)

  2. Article

    Open Access

    Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats

    Neurotrophic factors (NTFs) hold potential as disease-modifying therapies for neurodegenerative disorders like Parkinson’s disease. Glial cell line-derived neurotrophic factor (GDNF), cerebral dopamine neurot...

    Juho-Matti Renko, Susanne Bäck, Merja H. Voutilainen… in Molecular Neurobiology (2018)

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  3. Article

    Open Access

    Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra

    The anti-inflammatory effect of the cerebral dopamine neurotrophic factor (CDNF) was shown recently in primary glial cell cultures, yet such effect remains unknown both in vivo and in 6-hydroxydopamine (6-OHDA) m...

    Rasajna Nadella, Merja H Voutilainen, Mart Saarma… in Journal of Neuroinflammation (2014)

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  4. Article

    Open Access

    The role of SorLA in neurotrophic activity and complex behavior

    Simon Glerup, Mart Saarma, Anders Nykjaer in Molecular Neurodegeneration (2013)

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