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  1. Article

    Open Access

    Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis

    One target of rheumatoid arthritis (RA) treatment is to achieve early sustained remission; over the long term, patients in sustained remission have less structural joint damage and physical disability. We eval...

    Paul Emery, Yoshiya Tanaka, Vivian P. Bykerk… in Rheumatology and Therapy (2023)

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  2. Article

    Open Access

    HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA

    Certain risk alleles associated with autoantibody-positive rheumatoid arthritis (RA) have been linked to poorer prognoses. In patients with autoantibody-positive RA, abatacept shows differential efficacy to tu...

    William Rigby, Jane H. Buckner, S. Louis Bridges Jr… in Arthritis Research & Therapy (2021)

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  3. No Access

    Article

    Abatacept: A Review of the Treatment of Polyarticular-Course Juvenile Idiopathic Arthritis

    Juvenile idiopathic arthritis (JIA) encompasses several forms of chronic inflammatory arthritis of unknown etiology presenting in children < 16 years of age, with a minimum symptom duration of 6 weeks. Approxi...

    Hermine I. Brunner, Robert Wong, Marleen Nys, Tzuyung D. Kou… in Pediatric Drugs (2020)

  4. Article

    Open Access

    Maintenance of antibody response to diphtheria/tetanus vaccine in patients aged 2–5 years with polyarticular-course juvenile idiopathic arthritis receiving subcutaneous abatacept

    Patients with polyarticular-course juvenile idiopathic arthritis (pJIA), receiving disease-modifying anti-rheumatic drugs with immunosuppressive effects, may be at increased risk of vaccine-preventable infecti...

    Hermine I. Brunner, Nikolay Tzaribachev, Gabriel Vega Cornejo… in Pediatric Rheumatology (2020)

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