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    Open Access

    Allosteric control of Ubp6 and the proteasome via a bidirectional switch

    The proteasome recognizes ubiquitinated proteins and can also edit ubiquitin marks, allowing substrates to be rejected based on ubiquitin chain topology. In yeast, editing is mediated by deubiquitinating enzym...

    Ka Ying Sharon Hung, Sven Klumpe, Markus R. Eisele in Nature Communications (2022)