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Article
Open AccessGene-by-environment interactions in urban populations modulate risk phenotypes
Uncovering the interaction between genomes and the environment is a principal challenge of modern genomics and preventive medicine. While theoretical models are well defined, little is known of the G × E inter...
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Article
Open AccessEvaluation of daily time spent in transportation and traffic-influenced microenvironments by urban Canadians
Exposure to traffic and traffic-related air pollution is associated with a wide array of health effects. Time spent in a vehicle, in active transportation, along roadsides, and in close proximity to traffic ca...
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Article
Open AccessUpper gastrointestinal bleeding due to peptic ulcer disease is not associated with air pollution: a case-crossover study
Recent studies have demonstrated an association between short-term elevations in air pollution and an increased risk of exacerbating gastrointestinal disease. The objective of the study was to evaluate if day-...
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Article
Open AccessWithin- and between-city contrasts in nitrogen dioxide and mortality in 10 Canadian cities; a subset of the Canadian Census Health and Environment Cohort (CanCHEC)
The independent and joint effects of within- and between-city contrasts in air pollution on mortality have been investigated rarely. To examine the differential effects of between- versus within-city contrasts in...
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Article
Development of temporally refined land-use regression models predicting daily household-level air pollution in a panel study of lung function among asthmatic children
Regulatory monitoring data and land-use regression (LUR) models have been widely used for estimating individual exposure to ambient air pollution in epidemiologic studies. However, LUR models lack fine-scale t...
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Chapter and Conference Paper
Development and Evaluation of Land-Use Regression Models Using Modeled Air Quality Concentrations
Land-use regression (LUR) models have emerged as a preferred methodology for estimating individual exposure to ambient air pollution in epidemiologic studies in absence of subject-specific measurements. Althou...
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Article
Open AccessMechanistic Indicators of Childhood Asthma (MICA) Study: piloting an integrative design for evaluating environmental health
Asthma is a common complex disease responsible for considerable morbidity and mortality, particularly in urban minority populations. The Mechanistic Indicators of Childhood Asthma study was designed to pilot a...
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Article
Asthma, Environmental Risk Factors, and Hypertension Among Arab Americans in Metro Detroit
Asthma and obesity-related health problems disproportionately impact low-income ethnic minority communities residing in urban areas. Environmental risk factors, particularly those related to housing and indoor...
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Article
A participant-based approach to indoor/outdoor air monitoring in community health studies
Community health studies of traffic-related air pollution have been hampered by the cost and participant burden associated with collecting household-level exposure data. The current study utilized a participan...
