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  1. No Access

    Chapter and Conference Paper

    Resolving Multicopy Duplications de novo Using Polyploid Phasing

    While the rise of single-molecule sequencing systems has enabled an unprecedented rise in the ability to assemble complex regions of the genome, long segmental duplications in the genome still remain a challen...

    Mark J. Chaisson, Sudipto Mukherjee in Research in Computational Molecular Biology (2017)

  2. Article

    Open Access

    Map** single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory

    Recent methods have been developed to perform high-throughput sequencing of DNA by Single Molecule Sequencing (SMS). While Next-Generation sequencing methods may produce reads up to several hundred bases long,...

    Mark J Chaisson, Glenn Tesler in BMC Bioinformatics (2012)