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Article
Open AccessPI-QUAL version 2: an update of a standardised scoring system for the assessment of image quality of prostate MRI
Multiparametric MRI is the optimal primary investigation when prostate cancer is suspected, and its ability to rule in and rule out clinically significant disease relies on high-quality anatomical and function...
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Article
Open AccessProstate cancer detection and complications of MRI-targeted prostate biopsy using cognitive registration, software-assisted image fusion or in-bore guidance: a systematic review and meta-analysis of comparative studies
Three primary strategies for MRI-targeted biopsies (TB) are available: Cognitive TB (COG-TB), MRI-US Fusion TB (FUS-TB), and In Bore TB (IB-TB). Despite nearly a decade of practice, a consensus on the preferre...
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Article
Open AccessHigh-intensity focused ultrasound with visually directed power adjustment for focal treatment of localized prostate cancer: systematic review and meta-analysis
To characterize patient outcomes following visually directed high-intensity focused ultrasound (HIFU) for focal treatment of localized prostate cancer.
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Article
From BPH to male LUTS: a 20-year journey of the EAU guidelines
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Article
Prostatic high-resolution micro-ultrasound: an attractive step-forward in the management of prostate cancer patients
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Article
Diagnostic potential of radiological apical tumor involvement
We commend Veerman et al. for investigating the diagnostic performance of radiological apical tumor involvement (radATI) in preoperative prostate magnetic resonance imaging (MRI) and its impact on clinical out...
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Article
Open AccessPromoting the use of the PI-QUAL score for prostate MRI quality: results from the ESOR Nicholas Gourtsoyiannis teaching fellowship
The Prostate Imaging Quality (PI-QUAL) score is a new metric to evaluate the diagnostic quality of multiparametric magnetic resonance imaging (MRI) of the prostate. This study assesses the impact of an interve...
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Chapter and Conference Paper
Non-rigid Medical Image Registration using Physics-informed Neural Networks
Biomechanical modelling of soft tissue provides a non-data-driven method for constraining medical image registration, such that the estimated spatial transformation is considered biophysically plausible. This ...
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Article
Open AccessRenal tumouroids: challenges of manufacturing 3D cultures from patient derived primary cells
Recent advancements in 3D in vitro culture have allowed for the development of cancer tissue models which accurately recapitulate the tumour microenvironment. Consequently, there has been increased innovation ...
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Article
Open AccessPromoting the use of the PRECISE score for prostate MRI during active surveillance: results from the ESOR Nicholas Gourtsoyiannis teaching fellowship
The PRECISE criteria for serial multiparametric magnetic resonance imaging (MRI) of the prostate during active surveillance recommend the use of a dedicated scoring system (PRECISE score) to assess the likelih...
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Article
Open AccessProstate cancer and the human papilloma virus: causative association, role of vaccines, and the impact of the COVID-19 pandemic
Prostate cancer affects a significant proportion of men worldwide. Evidence from genetic and clinical studies suggests that there may be a causal association between prostate cancer and the human papilloma vir...
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Article
Open AccessInter-reader agreement of the PI-QUAL score for prostate MRI quality in the NeuroSAFE PROOF trial
The Prostate Imaging Quality (PI-QUAL) score assesses the quality of multiparametric MRI (mpMRI). A score of 1 means all sequences are below the minimum standard of diagnostic quality, 3 implies that the scan ...
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Chapter and Conference Paper
The Impact of Using Voxel-Level Segmentation Metrics on Evaluating Multifocal Prostate Cancer Localisation
Dice similarity coefficient (DSC) and Hausdorff distance (HD) are widely used for evaluating medical image segmentation. They have also been criticised, when reported alone, for their unclear or even misleadin...
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Article
Open AccessMap** PSA density to outcome of MRI-based active surveillance for prostate cancer through joint longitudinal-survival models
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Article
Conventional radical versus focal treatment for localised prostate cancer: a propensity score weighted comparison of 6-year tumour control
For localised prostate cancer, focal therapy offers an organ-sparing alternative to radical treatments (radiotherapy or prostatectomy). Currently, there is no randomised comparative effectiveness data evaluati...
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Article
Open AccessMultiparametric prostate MRI quality assessment using a semi-automated PI-QUAL software program
The technical requirements for the acquisition of multiparametric magnetic resonance imaging (mpMRI) of the prostate have been clearly outlined in the Prostate Imaging Reporting and Data System (PI-RADS) guide...
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Article
Cellular senescence as a possible link between prostate diseases of the ageing male
Senescent cells accumulate with age in all tissues. Although senescent cells undergo cell-cycle arrest, these cells remain metabolically active and their secretome — known as the senescence-associated secretor...
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Article
Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score-matched study
Focal therapy (FT) ablates areas of prostate cancer rather than treating the whole gland. We compared oncological outcomes of FT to radical prostatectomy (RP).
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Article
Open AccessUnderstanding PI-QUAL for prostate MRI quality: a practical primer for radiologists
Prostate magnetic resonance imaging (MRI) of high diagnostic quality is a key determinant for either detection or exclusion of prostate cancer. Adequate high spatial resolution on T2-weighted imaging, good dif...
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Article
Open AccessFocal HIFU therapy for anterior compared to posterior prostate cancer lesions
To compare cancer control in anterior compared to posterior prostate cancer lesions treated with a focal HIFU therapy approach.
