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Comparing neoadjuvant therapy followed by local excision to total mesorectal excision in the treatment of early stage rectal cancer: a systematic review and meta-analysis of randomised clinical trials

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  1. Article

    Open Access

    Evaluating the oncological safety of neoadjuvant chemotherapy in locally advanced colon carcinoma: a systematic review and meta-analysis of randomised clinical trials and propensity-matched studies

    Use of neoadjuvant chemotherapy (NAC) for locally advanced colon cancer (LACC) remains controversial. An integrated analysis of data from high-quality studies may inform the long-term safety of NAC for this co...

    Matthew G. Davey, Amira H. Amir in International Journal of Colorectal Disease (2023)

  2. Article

    Impact of model misspecification on model-based tests in PK studies with parallel design: real case and simulation studies

    This article evaluates the performance of pharmacokinetic (PK) equivalence testing between two formulations of a drug through the Two-One Sided Tests (TOST) by a model-based approach (MB-TOST), as an alternati...

    Mélanie Guhl, François Mercier in Journal of Pharmacokinetics and Pharmacody… (2022)

  3. Chapter and Conference Paper

    Choosing the Most Suitable Classifier for Supporting Assistive Technology Adoption in People with Parkinson’s Disease: A Fuzzy Multi-criteria Approach

    Parkinson’s disease (PD) is the second most common neurodegenerative disorder which requires a long-term, interdisciplinary disease management. While there remains no cure for Parkinson’s disease, treatments a...

    Miguel Ortíz-Barrios, Ian Cleland in Digital Human Modeling and Applications in… (2020)

  4. Article

    Open Access

    Indoor localisation through object detection within multiple environments utilising a single wearable camera

    The recent growth in the wearable sensor market has stimulated new opportunities within the domain of Ambient Assisted Living, providing unique methods of collecting occupant information. This approach leverag...

    Colin Shewell, Chris Nugent, Mark Donnelly, Haiying Wang in Health and Technology (2017)

  5. Article

    The impact of solutions for chronic disease prevention and management

    Mark Donnelly, Chris Nugent, Cristiano Paggetti in Health and Technology (2013)