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Article
Sepsis-trained macrophages promote antitumoral tissue-resident T cells
Sepsis induces immune alterations, which last for months after the resolution of illness. The effect of this immunological reprogramming on the risk of develo** cancer is unclear. Here we use a national clai...
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Article
Open AccessRUFY3 regulates endolysosomes perinuclear positioning, antigen presentation and migration in activated phagocytes
Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing p...
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Article
Author Correction: Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis
Sepsis and trauma cause inflammation and elevated susceptibility to hospital-acquired pneumonia. As phagocytosis by macrophages plays a critical role in the control of bacteria, we investigated the phagocytic ...
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Article
Open AccessInterleukin-22 level is negatively correlated with neutrophil recruitment in the lungs in a Pseudomonas aeruginosa pneumonia model
Pseudomonas aeruginosa is a major threat for immune-compromised patients. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respir...
