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Article
Open AccessThe greenbeard gene tgrB1 regulates altruism and cheating in Dictyostelium discoideum
Greenbeard genetic elements encode rare perceptible signals, signal recognition ability, and altruism towards others that display the same signal. Putative greenbeards have been described in various organisms ...
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Article
Open AccessThe GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium
In many systems, including the social amoeba Dictyostelium discoideum, development is often marked by dynamic morphological and transcriptional changes orchestrated by key transcription factors. However, efforts ...
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Article
Open AccessLeaps and lulls in the developmental transcriptome of Dictyostelium discoideum
Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by t...
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Transcriptional Regulators: Dynamic Drivers of Multicellular Formation, Cell Differentiation and Development
In this chapter, we examine what is known about the roles of individual transcription regulators in mediating development in Dictyostelium discoideum. We present a broad review of the field, covering genetic, bio...
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Article
Open AccessComparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum
The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk ce...
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Article
Open AccessConserved developmental transcriptomes in evolutionarily divergent species
Evolutionarily divergent organisms often share developmental anatomies despite vast differences between their genome sequences. The social amoebae Dictyostelium discoideum and Dictyostelium purpureum have similar...