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  1. Article

    Open Access

    The greenbeard gene tgrB1 regulates altruism and cheating in Dictyostelium discoideum

    Greenbeard genetic elements encode rare perceptible signals, signal recognition ability, and altruism towards others that display the same signal. Putative greenbeards have been described in various organisms ...

    Mariko Katoh-Kurasawa, Peter Lehmann, Gad Shaulsky in Nature Communications (2024)

  2. Article

    Open Access

    The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium

    In many systems, including the social amoeba Dictyostelium discoideum, development is often marked by dynamic morphological and transcriptional changes orchestrated by key transcription factors. However, efforts ...

    Balaji Santhanam, Huaqing Cai, Peter N. Devreotes, Gad Shaulsky in Nature Communications (2015)

  3. Article

    Open Access

    Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum

    Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by t...

    Rafael David Rosengarten, Balaji Santhanam, Danny Fuller in BMC Genomics (2015)

  4. No Access

    Chapter

    Transcriptional Regulators: Dynamic Drivers of Multicellular Formation, Cell Differentiation and Development

    In this chapter, we examine what is known about the roles of individual transcription regulators in mediating development in Dictyostelium discoideum. We present a broad review of the field, covering genetic, bio...

    Rafael D. Rosengarten, Balaji Santhanam, Mariko Katoh-Kurasawa in Dictyostelids (2013)

  5. Article

    Open Access

    Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum

    The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk ce...

    Richard Sucgang, Alan Kuo, **angjun Tian, William Salerno, Anup Parikh in Genome Biology (2011)

  6. Article

    Open Access

    Conserved developmental transcriptomes in evolutionarily divergent species

    Evolutionarily divergent organisms often share developmental anatomies despite vast differences between their genome sequences. The social amoebae Dictyostelium discoideum and Dictyostelium purpureum have similar...

    Anup Parikh, Edward Roshan Miranda, Mariko Katoh-Kurasawa, Danny Fuller in Genome Biology (2010)