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Open AccessVimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress
The intermediate filament (IF) cytoskeleton has been proposed to regulate morphogenic processes by integrating the cell fate signaling machinery with mechanical cues. Signaling between endothelial cells (ECs) ...
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Article
PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner
Activation of Notch signaling requires intracellular routing of the receptor, but the mechanisms controlling the distinct steps in the routing process is poorly understood. We identify PKCζ as a key regulator ...
