20 Result(s)

Article

Predictors of High Healthcare Cost Among Patients with Generalized Myasthenia Gravis: A Combined Machine Learning and Regression Approach from a US Payer Perspective

High healthcare costs could arise from unmet needs. This study used random forest (RF) and regression methods to identify predictors of high costs from a US payer perspective in patients newly diagnosed with g...

Maryia Zhdanava, Jacqueline Pesa… in Applied Health Economics and Health Policy (2024)

Article

A Cross-Sectional Study of Patient Out-of-Pocket Costs for Antipsychotics Among Medicaid Beneficiaries with Schizophrenia

Patient affordability is an important nonclinical consideration for treatment access among patients with schizophrenia.

Dee Lin, Dominic Pilon, Laura Morrison, Aditi Shah… in Drugs - Real World Outcomes (2023)

Article

Healthcare Resource Utilization and Costs in Patients with EGFR-Mutated Advanced Non-Small Cell Lung Cancer Receiving First-Line Treatment in the United States: An Insurance Claims-Based Descriptive Analysis

An estimated 10–15% of non-small cell lung cancer (NSCLC) cases present with epidermal growth factor receptor mutation (EGFRm). While EGFR tyrosine kinase inhibitors (EGFR-TKIs) such as osimertinib have become...

Julie Vanderpoel, Bruno Emond, Isabelle Ghelerter… in PharmacoEconomics - Open (2023)

Article

Comparison of clinical outcomes in patients with schizophrenia following different long-acting injectable event-driven initiation strategies

This retrospective study evaluated the benefit of following different long-acting injectable (LAI) initiation strategies based on the timing of behavioral and clinical events among Medicaid beneficiaries with ...

Christoph U. Correll, Carmela Benson, Bruno Emond, Charmi Patel… in Schizophrenia (2023)

Article

Association Between Weight Gain and the Incidence of Cardiometabolic Conditions Among People Living with HIV-1 at High Risk of Weight Gain Initiated on Antiretroviral Therapy

Antiretroviral therapy (ART) has been associated with weight gain in people living with HIV-1 (PLWH); however, limited research has assessed whether early weight gain post-ART initiation is associated with met...

Grace A. McComsey, Bruno Emond, Aditi Shah… in Infectious Diseases and Therapy (2022)

Article

Real-World Effectiveness of Newly Initiated Systemic Therapy for Atopic Dermatitis in the United States: A Claims Database Analysis

Atopic dermatitis (AD) is associated with significant quality-of-life and economic burdens. Real-world evidence is needed to identify optimal treatment pathways for AD. Here we evaluate real-world effectivenes...

Jashin J. Wu, Marie-Hélène Lafeuille, Bruno Emond, Iman Fakih… in Advances in Therapy (2022)

Article

Correction to: Treatment patterns and effectiveness of patients with multiple myeloma initiating Daratumumab across different lines of therapy: a real-world chart review study

Shebli Atrash, Philippe Thompson-Leduc, Ming-Hui Tai, Shuchita Kaila… in BMC Cancer (2021)

Article

Treatment patterns and effectiveness of patients with multiple myeloma initiating Daratumumab across different lines of therapy: a real-world chart review study

Daratumumab, a CD38 monoclonal antibody, has demonstrated efficacy as monotherapy and combination therapy across several indications, both among newly-diagnosed and refractory patients with multiple myeloma (M...

Shebli ATRASH, Philippe THOMPSON-LEDUC, Ming-Hui TAI, Shuchita KAILA… in BMC Cancer (2021)

Article

Correction to: Real-World Evidence of the Clinical and Economic Impact of Long-Acting Injectable Versus Oral Antipsychotics Among Patients with Schizophrenia in the United States: A Systematic Review and Meta-Analysis

Dee Lin, Philippe Thompson-Leduc, Isabelle Ghelerter, Ha Nguyen… in CNS Drugs (2021)

Article

Real-World Utilization and Safety of Daratumumab IV Rapid Infusions Administered in a Community Setting: A Retrospective Observational Study

Some institutions have implemented a daratumumab intravenous rapid-infusion protocol in which patients with multiple myeloma (MM) receive their third and subsequent infusions within ~ 90 min instead of ≥ 3 h.

Lucio Gordan, Melody Chang, Marie-Hélène Lafeuille… in Drugs - Real World Outcomes (2021)

Article

Real-World Evidence of the Clinical and Economic Impact of Long-Acting Injectable Versus Oral Antipsychotics Among Patients with Schizophrenia in the United States: A Systematic Review and Meta-Analysis

Long-acting injectable (LAI) antipsychotics, compared with oral antipsychotics (OA), have been found to significantly improve patient outcomes, including reduced hospitalizations and emergency room (ER) admiss...

Dee Lin, Philippe Thompson-Leduc, Isabelle Ghelerter, Ha Nguyen… in CNS Drugs (2021)

Article

Real-World Analysis of Switching Patients with Schizophrenia from Oral Risperidone or Oral Paliperidone to Once-Monthly Paliperidone Palmitate

Reducing the dosing frequency of antipsychotics (APs) with long-acting injectables (LAIs) such as once-monthly paliperidone palmitate (PP1M) can improve adherence and clinical outcomes for schizophrenia patien...

Charmi Patel, Bruno Emond, Marie-Hélène Lafeuille… in Drugs - Real World Outcomes (2020)

Article

Adherence, Healthcare Resource Utilization, and Costs in Medicaid Beneficiaries with Schizophrenia Transitioning from Once-Monthly to Once-Every-3-Months Paliperidone Palmitate

The aim was to compare adherence to antipsychotics (APs), healthcare resource utilization (HRU), and costs before and after once-every-3-months paliperidone palmitate (PP3M) initiation in patients with schizop...

Bruno Emond, Kruti Joshi, Antoine C. El Khoury… in PharmacoEconomics - Open (2019)

Article

Development of predictive risk models for major adverse cardiovascular events among patients with type 2 diabetes mellitus using health insurance claims data

There exist several predictive risk models for cardiovascular disease (CVD), including some developed specifically for patients with type 2 diabetes mellitus (T2DM). However, the models developed for a diabeti...

James B. Young, Marjolaine Gauthier-Loiselle… in Cardiovascular Diabetology (2018)

Article

Economic Impact in Medicaid Beneficiaries with Schizophrenia and Cardiometabolic Comorbidities Treated with Once-Monthly Paliperidone Palmitate vs. Oral Atypical Antipsychotics

The objective of this study was to compare persistence, costs, and healthcare resource utilization in patients with schizophrenia and cardiometabolic comorbidities treated with once-monthly paliperidone palmit...

Marie-Hélène Lafeuille, Neeta Tandon, Sean Tiggelaar… in Drugs - Real World Outcomes (2018)

Article

Quality measure and weight loss assessment in patients with type 2 diabetes mellitus treated with canagliflozin or dipeptidyl peptidase-4 inhibitors

Achieving control of glycated hemoglobin (HbA1c), blood pressure (BP), and body weight (BW) remains a challenge for most patients with type 2 diabetes mellitus (T2DM). In clinical trials, canagliflozin (CANA),...

Carol H. Wysham, Patrick Lefebvre, Dominic Pilon, Mike Ingham… in BMC Endocrine Disorders (2017)

Article

Impact of atypical long-acting injectable versus oral antipsychotics on rehospitalization rates and emergency room visits among relapsed schizophrenia patients: a retrospective database analysis

Among schizophrenia patients relapsed on an oral antipsychotic (AP), this study compared the impact of switching to atypical AP long-acting injectable therapy (LAT) versus continuing oral APs on hospitalizatio...

Marie-Hélène Lafeuille, François Laliberté-Auger, Patrick Lefebvre… in BMC Psychiatry (2013)