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Protocol
How to Assess and Study Cell Death in Dictyostelium discoideum
In this chapter, we describe how to conveniently demonstrate, assess, and study cell death in Dictyostelium through simple cell culture, clonogenic tests, and photonic (with the help of staining techniques) and e...
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Chapter
Mammalian ABC Transporters and Leaderless Secretion: Facts and Speculations
ABC transporters are one of the largest family of membrane transporters extremely conserved across evolution, from bacteria to mammals. Most of the members of the family function as ATP-dependent active transp...
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Article
A new member of the immunoglobulin superfamily—CTLA-4
The immunoglobulin superfamily is a group of proteins, each made of one or several domains sharing key structural features with either the variable (V) or the constant (C) immunoglobulin domains1,2. It includes s...
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Article
The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14
Classical phenomenological approaches to the study of the mechanism of T-cell-mediated cytotoxicity1–3 have now given way to a search for molecules involved in this function; this is attempted either by subcellul...