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Article
Ischemic myocardial injury in cultured heart cells: Preliminary observations on morphology and beating activity
An in vitro model of myocardial ischemia has been established with primary monolayer cultures of neonatal rat heart cells. Ischemic conditions were simulated in vitro by subjecting the heart cell cultures to v...
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Article
Ischemic myocardial injury in cultured heart cells: Leakage of cytoplasmic enzymes from injured cells
An in vitro model of myocardial ischemia has been established with primary monolayer cultures of postnatal rat myocardial cells. Ischemic conditions were simulated in vitro by subjecting the myocardial cell cu...
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Article
Ischemic myocardial injury in cultured heart cells: In situ lysosomal damage
Primary cultures of rat myocardial cells which were subjected to oxygen and glucose deprivation, 2 conditions associated with ischemia, were evaluated for alterations in lysosomal integrity. A photometric tech...
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Article
Reduction of cell injury in hypoxic cultures of rat myocardial cells by methylprednisolone
An in vitro model to study myocardial cell injury was developed with primary monolayer cultures of rat myocardial cells. Two important conditions associated with myocardial ischemia were simulated by depriving...
