5 Result(s)
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Maria-Giuseppina Procopio
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Article
Open AccessFully automated sequential immunofluorescence (seqIF) for hyperplex spatial proteomics
Tissues are complex environments where different cell types are in constant interaction with each other and with non-cellular components. Preserving the spatial context during proteomics analyses of tissue sam...
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Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study
Breast cancer is a highly heterogeneous disease. The efficacy of tailored therapeutic strategies relies on the precise detection of diagnostic biomarkers by immunohistochemistry (IHC). Therefore, considering t...
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Open AccessMicrofluidics-based immunofluorescence for fast staining of ALK in lung adenocarcinoma
Anaplastic lymphoma kinase (ALK) is a key oncogenic driver in lung adenocarcinoma patients and its fusion proteins are routinely assessed. The microfluidic tissue processor (MTP) device is based on a chip-confine...
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Correction: Corrigendum: Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
Nat. Cell Biol. 17, 1193–1204 (2015); published online 24 August 2015; corrected after print 28 August 2015 An error in the print version of this Article meant that Witold W. Kilarski's name was incorrect. Thi...
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Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
Stromal fibroblast senescence has been linked to ageing-associated cancer risk. However, density and proliferation of cancer-associated fibroblasts (CAFs) are frequently increased. Loss or downmodulation of th...
