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Article
Adult primary nephrotic syndrome trends by race: a diminished frequency of focal segmental glomerulosclerosis in non-black patients
There have been conflicting data on the relative frequency of common forms of primary nephrotic syndrome (PNS). We undertook this study to look at the causes of PNS in the latest decade from our biopsy populat...
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Chronic Kidney Disease – Mineral and Bone Disorder (CKD-MBD)
Declining kidney function results in mineral and hormonal imbalances that trigger a maladaptive feedback loop favoring the oversecretion of parathyroid hormone (PTH). As kidney disease progresses, chronic hype...
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Article
Use of lung ultrasonography to determine the accuracy of clinically estimated dry weight in chronic hemodialysis patients
The use of lung ultrasound (LUS) to identify extravascular lung water has received increasing acceptance. Sonographic B-lines, discrete vertical lines that originate from the pleura, represent pulmonary edema ...
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Article
Oral vitamin C supplementation reduces erythropoietin requirement in hemodialysis patients with functional iron deficiency
Functional iron deficiency (FID) is a major cause of persistent anemia in dialysis patients and also contributes to a suboptimal response to erythropoietin (Epo) administration. Vitamin C acts as an enzyme cof...
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Article
Preventing the progression of chronic kidney disease: two case reports and review of the literature
A variety of therapeutic modalities are available to alter the abnormalities seen in patients with chronic kidney disease (CKD). A comprehensive plan can now be developed to slow the progression of CKD. Two cl...
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Article
Characteristics, therapies, and factors influencing outcomes of hospitalized hypernatremic geriatric patients
Hypernatremia is a common electrolyte disorder associated with adverse outcomes such as increased length of stay and mortality due to a variety of factors. Our aim was to investigate known factors as well as o...
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Article
Troponin I as a prognostic marker of cardiac events in asymptomatic hemodialysis patients using a sensitive troponin I assay
Elevated troponin T is known to be a prognostic marker for long-term cardiac events and mortality in asymptomatic end-stage renal disease patients. There are conflicting data in this regard with respect to tro...
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Article
Serum and urine responses to the aquaretic agent tolvaptan in hospitalized hyponatremic patients
Tolvaptan, an oral, selective arginine vasopressin (AVP) V2 receptor antagonist has been approved for the treatment of euvolemic and hypervolemic hyponatremia in the United States. This report summarizes our c...
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Article
Impact of heart failure on the incidence of contrast-induced nephropathy in patients with chronic kidney disease
We randomized patients with chronic kidney disease (serum creatinine ≥ 1.5 mg/dl or glomerular filtration rate (GFR) <60 ml/min/1.73 m²) in a double-blind fashion to receive saline or sodium bicarbonate prior ...
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Article
Hyponatremia associated with large-bone fracture in elderly patients
Hyponatremia has been shown to be associated with gait disturbances, decreased mentation, and falls. The study objective was to determine the incidence of hyponatremia in patients who experienced a substantial...
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Article
Observations regarding the use of the aquaretic agent conivaptan for treatment of hyponatremia
The treatment of hyponatremia, especially euvolemic and hypervolemic hyponatremia, has changed with the development of drugs which function as vasopressin receptor antagonists. These agents increase solute-fre...
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Article
The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy
The effect of continuing or discontinuing chronic angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) therapy prior to coronary angiography on the incidence of contrast-induced...
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Article
Pregnancy in Peritoneal Dialysis: A Case Report and Review of Adequacy and Outcomes
A case of pregnancy in a 27-year-old woman on peritoneal dialysis is presented. The case report is a detailed description of her course including changes in her peritoneal dialysis regimen and the use of conti...
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Article
Failure of intravenous fluid therapies to decrease serum sodium levels in elderly hospitalized patients
Elderly patients may have a tendency to develop hyponatremia due to sensitivity to stimuli that release ADH as well as an impaired ability to excrete a water load. We evaluated changes in serum sodium in elder...
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Article
Drug use and the elderly in relation to changing etiologies of hyperkalemia
Since there has been an increase in the use of medications known to change renal potassium handling, we reassessed the prevalence of and factors associated with hyperkalemia (potassium ≧ 5.1 mmol L−1) in 100 hosp...