![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
In March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by f...
-
Article
Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
-
Article
2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales
In March 2020, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. At the genus rank, 20 new ge...
-
Article
Taxonomy of the order Bunyavirales: update 2019
In February 2019, following the annual taxon ratification vote, the order Bunyavirales was amended by creation of two new families, four new subfamilies, 11 new genera and 77 new species, merging of two species, ...
-
Article
Taxonomy of the order Bunyavirales: second update 2018
In October 2018, the order Bunyavirales was amended by inclusion of the family Arenaviridae, abolishment of three families, creation of three new families, 19 new genera, and 14 new species, and renaming of three...
-
Article
Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018
In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species. This article presents the up...
-
Protocol
Diagnostics for Lassa Fever: Detecting Host Antibody Responses
There are two types of viral diagnostics: (1) those that detect components of the pathogen (like viral RNA or proteins) and (2) those that detect host molecules that rise or fall as a consequence of pathogen i...
-
Protocol
A Primate Model for Viral Hemorrhagic Fever
Lymphocytic choriomeningitis virus strain WE (LCMV-WE), a Risk Group 3 virus, causes a disease in rhesus monkeys that closely resembles human infection with Lassa fever virus, a Risk Group 4 agent. Three stage...
-
Article
Past, present, and future of arenavirus taxonomy
Until recently, members of the monogeneric family Arenaviridae (arenaviruses) have been known to infect only muroid rodents and, in one case, possibly phyllostomid bats. The paradigm of arenaviruses exclusively i...
-
Article
Open AccessAn attenuated Lassa vaccine in SIV-infected rhesus macaques does not persist or cause arenavirus disease but does elicit Lassa virus-specific immunity
Lassa hemorrhagic fever (LHF) is a rodent-borne viral disease that can be fatal for human beings. In this study, an attenuated Lassa vaccine candidate, ML29, was tested in SIV-infected rhesus macaques for its ...
-
Article
Open AccessRole of the Fas/FasL Pathway in HIV or SIV Disease
Human immunodeficiency virus disease involves progressive destruction of host immunity leading to opportunistic infections and increased rates for malignancies. Quantitative depletion of immune cell subsets an...
-
Article
Open AccessGene expression in primate liver during viral hemorrhagic fever
Rhesus macaques infected with lymphocytic choriomeningitis virus (LCMV) provide a model for human Lassa fever. Disease begins with flu-like symptoms and progresses rapidly with fatal consequences. Previously, ...
-
Article
Molecular characterization of a reassortant virus derived from Lassa and Mopeia viruses
In this article we describe two new complete genomic sequences of Old World Arenaviruses: the Mopeia (MOP) virus and the reassortant MOP/LAS virus, clone 29, or ML29. This reassortant has the large (L) RNA fro...
-
Article
Open AccessProlonged AIDS-free Survival for SIV-infected Macaques Treated With Anti-FasL
-
Reference Work Entry In depth
Arenavirus
-
Article
Sequence Comparison of the Large Genomic RNA Segments of Two Strains of Lymphocytic Choriomeningitis Virus Differing in Pathogenic Potential for Guinea Pigs
Two strains of lymphocytic choriomeningitis virus (LCMV) differ in their ability to cause a lethal disease in outbred guinea pigs: the Armstrong (ARM) strain is not lethal at high doses (106 PFU), whereas the WE ...
-
Book
-
Chapter
Molecular Biology of the Prototype Arenavirus, Lymphocytic Choriomeningitis Virus
Structural analysis of a well-characterized virus such as lymphocytic choriomeningitis virus (LCMV) is of particular importance in interpret-ing complex biological phenomena. Complete determination of the nu-c...