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    Chapter and Conference Paper

    Formal Methods for Checking the Consistency of Biological Models

    Formal modeling approaches such as process algebras and Petri nets seek to provide insight into biological processes by using both symbolic and numerical methods to reveal the dynamics of the process under stu...

    Allan Clark, Vashti Galpin, Stephen Gilmore in Advances in Systems Biology (2012)

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    Chapter

    Translation from the Quantified Implicit Process Flow Abstraction in SBGN-PD Diagrams to Bio-PEPA Illustrated on the Cholesterol Pathway

    For a long time biologists have used visual representations of biochemical networks to gain a quick overview of important structural properties. Recently SBGN, the Systems Biology Graphical Notation, has been ...

    Laurence Loewe, Maria Luisa Guerriero in Transactions on Computational Systems Biol… (2011)

  3. Article

    Open Access

    Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway

    Appropriately formulated quantitative computational models can support researchers in understanding the dynamic behaviour of biological pathways and support hypothesis formulation and selection by "in silico" ...

    Maria Luisa Guerriero, Anna Dudka, Nicholas Underhill-Day in BMC Systems Biology (2009)

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    Chapter and Conference Paper

    Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network

    Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhythms of metabolism, physiology a...

    Ozgur E. Akman, Federica Ciocchetta in Computational Methods in Systems Biology (2009)

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    Chapter

    Qualitative and Quantitative Analysis of a Bio-PEPA Model of the Gp130/JAK/STAT Signalling Pathway

    Computational modelling of complex biochemical systems has grown in importance over recent years as a tool for supporting biological studies. Consequently, several formal languages have been recently proposed ...

    Maria Luisa Guerriero in Transactions on Computational Systems Biology XI (2009)

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    Chapter

    Process Calculi Abstractions for Biology

    Several approaches have been proposed to model biological systems by means of the formal techniques and tools available in computer science. To mention just a few of them, some representations are inspired by ...

    Maria Luisa Guerriero, Davide Prandi, Corrado Priami in Algorithmic Bioprocesses (2009)

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    Chapter and Conference Paper

    An Automated Translation from a Narrative Language for Biological Modelling into Process Algebra

    The aim of this work is twofold. First, we propose an high level textual modelling language, which is meant to be biologically intuitive and hence easily usable by life scientists in modelling intra-cellular s...

    Maria Luisa Guerriero, John K. Heath in Computational Methods in Systems Biology (2007)

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    Chapter and Conference Paper

    Modeling Static Biological Compartments with Beta-binders

    We investigate the modeling of biological systems with static compartments through Beta-binders, a recently developed process calculus. Biological entities are represented as bio-processes and the calculus is ...

    Maria Luisa Guerriero, Corrado Priami, Alessandro Romanel in Algebraic Biology (2007)