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Article
Proton Pump Inhibitor Use and the Risk of Cardiovascular Complications and Death in Older Adults with Diabetes: A Population-Based Cohort Study
The unfavorable effect of proton pump inhibitors (PPIs) on cardiovascular (CV) outcomes and mortality was reported in the general population. We investigated the impact of PPIs on CV outcomes and total mortali...
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Article
Open AccessImpact of chronic GLP-1 RA and SGLT-2I therapy on in-hospital outcome of diabetic patients with acute myocardial infarction
Glucagon-like peptide-1 receptor agonists (GLP-1 RA) and sodium glucose cotransporter-2 inhibitors (SGLT-2i) demonstrated cardiovascular and renal protection. Whether their benefits occur also during hospitali...
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Article
Open AccessDiabetes mellitus duration and mortality in patients hospitalized with acute myocardial infarction
Diabetes mellitus (DM) is associated with an increased mortality risk in patients hospitalized with acute myocardial infarction (AMI); however, no studies have investigated the impact of the duration of DM on ...
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Article
Open AccessEffectiveness and safety of GLP-1 receptor agonists versus SGLT-2 inhibitors in type 2 diabetes: an Italian cohort study
GLP-1 receptor agonists (GLP-1 RA) and SGLT-2 inhibitors (SGLT-2i) have shown to reduce the risk of major adverse cardiovascular events (MACE), death and worsening nephropathy when added to standard of care. H...
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Article
Temporal trends from 2005 to 2018 in deaths and cardiovascular events in subjects with newly diagnosed rheumatoid arthritis
Although rheumatoid arthritis (RA) is associated with an increased risk of death and cardiovascular (CV) disease, the excess of these risks is expected to have diminished over time, in more recent incident coh...
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Article
Sex-related differences in prevalence, treatment and outcomes in patients with atrial fibrillation
To analyze sex-related differences about AF prevalence, use of OAC and outcomes focusing on the older age classes. We used administrative data of the Lombardy Region, describing period prevalence, use of OAC a...
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Article
Open AccessAspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials
The clinical benefit of aspirin for the primary prevention of cardiovascular disease (CVD) in diabetes remains uncertain. To evaluate the efficacy and safety of aspirin for the primary prevention of cardiovasc...
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Article
Prevalence and management of diabetes in immigrants resident in the Lombardy Region: the importance of ethnicity and duration of stay
To describe the prevalence and management of diabetes among immigrants according to ethnic group and duration of stay, compared to Italian citizens.
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Article
Diabetes mellitus: a risk factor for seizures in the elderly—a population-based study
To evaluate the association between diabetes mellitus (DM) and risk of seizures in a well-defined elderly population.
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Article
Emergency department visits in older people: pattern of use, contributing factors, geographical differences and outcomes
To assess the pattern of use of Emergency Departments (EDs), factors contributing to the visits, geographical distribution and outcomes in people aged 65 years or more living in the Italian Lombardy Region in ...
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Article
Are all people with diabetes and cardiovascular risk factors or microvascular complications at very high risk? Findings from the Risk and Prevention Study
To verify whether it is possible, in people with diabetes mellitus (DM) considered at very high cardiovascular (CV) risk, stratify this risk better and identify significant modifiable risk factor (including li...
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Article
Comparison of Health Care Resource Utilization by Immigrants Versus Native Elderly People
To compare the utilization of health care resources (drug prescriptions, hospital admissions and health care services) by immigrant versus native elderly people (65 years or more), by using administrative data...
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Article
Changes in prescribing patterns and clinical outcomes in elderly diabetic patients in 2000 and 2010: analysis of a large Italian population-based study
To describe prescribing patterns in elderly Italian diabetic patients of the Lombardy Region in 2000 and 2010 using an administrative database. Hospital admissions and mortality were also recorded and compared...
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Article
Response to Naunton and Duyvendak re “Appropriate use of antiplatelets: is prescription in daily practice influenced by the global cardiovascular risk?”
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Article
Appropriate use of antiplatelets: is prescription in daily practice influenced by the global cardiovascular risk?
To evaluate the appropriate prescription of antiplatelets according to patients’ global cardiovascular risk level in everyday practice.
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Article
Open AccessLong-term vitamin E supplementation fails to reduce lipid peroxidation in people at cardiovascular risk: analysis of underlying factors
Antioxidant supplementation with vitamin E had no effect in the prevention of cardiovascular diseases (CVD) in three recent large, randomized clinical trials. In order to reassess critically the role of vitami...