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Article
Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, characterized by asthma, eosinophilia and granulomatous or vasculitic involveme...
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Article
Large-vessel vasculitis
Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches and is the most common primary vasculitis in adults. LVV comprises two distinct conditions, giant cell arteritis and ...
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Article
Open AccessThe receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma
Microenvironment contributes to follicular lymphoma (FL) pathogenesis and impacts survival with macrophages playing a controversial role. In the present study, using FL primary samples and HK follicular dendri...
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Article
Open AccessPrevalence of cardiovascular risk factors, the use of statins and of aspirin in Takayasu Arteritis
The aim of this study was to assess the prevalence of cardiovascular risk factors in TAK, to describe the use of aspirin and statins and the risk factors associated with vascular ischemic complications and rel...
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Article
Open AccessGenome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease of unknown cause. 30% of patients have anti-neutrophil cytoplasmic antibodies (ANCA) specific for myeloperoxidase (MPO). Here...
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Article
Open AccessCorrection: Corrigendum: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy
Scientific Reports 7: Article number: 43953; published online: 09 March 2017; updated: 05 April 2017 In this Article, Javier Martin is incorrectly listed as being affiliated with “Departamento de Genética e In...
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Article
Open AccessAnalysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy
Giant cell arteritis (GCA) and Takayasu’s arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotypin...
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Article
New insights into the molecular basis of systemic vasculitis
Gene variants have been discovered that cause a range of vascular inflammatory phenotypes with a characteristic onset in childhood. What might these exciting findings mean for the understanding, diagnosis and ...
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Article
The impact of 18F-FDG PET on the management of patients with suspected large vessel vasculitis
We aimed to assess the impact of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) on the management of patients with suspected large vessel vasculitis.
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Article
Estradiol enhances endothelial cell interactions with extracellular matrix proteins via an increase in integrin expression and function
Premenopausal women have a lower cardiovascular risk and a higher incidence of several autoimmune diseases involving blood vessels than men. Although the precise effects of estrogens on the cardiovascular syst...
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Article
T-cell population of primary and secondary cutaneous B-cell lymphomas does not express the cutaneous lymphocyte-associated antigen (CLA)
