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    Article

    Identifying keystone species in microbial communities using deep learning

    Previous studies suggested that microbial communities can harbour keystone species whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an efficient method to systematically i...

    Xu-Wen Wang, Zheng Sun, Huijue Jia, Sebastian Michel-Mata in Nature Ecology & Evolution (2024)

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    Modeling SARS-CoV-2: Mitigation Interventions and Increased Mobility Events

    From the beginning of the SARS-CoV-2 pandemic, mathematical models have been developed to describe, predict, and control its evolution. This chapter presents a set of useful mathematical tools to understand th...

    Mario Santana-Cibrian in Modeling, Control and Drug Development for… (2022)

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    Article

    Coexistence holes characterize the assembly and disassembly of multispecies systems

    A central goal of ecological research has been to understand the limits on the maximum number of species that can coexist under given constraints. However, we know little about the assembly and disassembly pro...

    Marco Tulio Angulo, Aaron Kelley, Luis Montejano in Nature Ecology & Evolution (2021)

  4. Article

    Open Access

    Generalizing game-changing species across microbial communities

    Microbes form multispecies communities that play essential roles in our environment and health. Not surprisingly, there is an increasing need for understanding if certain invader species will modify a given mi...

    Jie Deng, Marco Tulio Angulo, Serguei Saavedra in ISME Communications (2021)

  5. Article

    Open Access

    An ecological framework to understand the efficacy of fecal microbiota transplantation

    Human gut microbiota plays critical roles in physiology and disease. Our understanding of ecological principles that govern the dynamics and resilience of this highly complex ecosystem remains rudimentary. Thi...

    Yandong **ao, Marco Tulio Angulo, Songyang Lao, Scott T. Weiss in Nature Communications (2020)

  6. Article

    Open Access

    A theoretical framework for controlling complex microbial communities

    Microbes form complex communities that perform critical roles for the integrity of their environment or the well-being of their hosts. Controlling these microbial communities can help us restore natural ecosys...

    Marco Tulio Angulo, Claude H. Moog, Yang-Yu Liu in Nature Communications (2019)

  7. Article

    Open Access

    Map** the ecological networks of microbial communities

    Map** the ecological networks of microbial communities is a necessary step toward understanding their assembly rules and predicting their temporal behavior. However, existing methods require assuming a parti...

    Yandong **ao, Marco Tulio Angulo, Jonathan Friedman in Nature Communications (2017)

  8. Article

    Network motifs emerge from interconnections that favour stability

    Small distinctive patterns or ‘motifs’ are more prevalent in real systems than they are in randomly generated networks. It now seems that these motifs emerge naturally according to a principle that favours int...

    Marco Tulio Angulo, Yang-Yu Liu, Jean-Jacques Slotine in Nature Physics (2015)