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Article
Comparison of purse-string technique vs linear suture for skin closure after ileostomy reversal. A randomized controlled trial
Protective stoma after rectal surgery has been associated with important complications. The most common is surgical site infection (SSI) high rates after stoma reversal reported in literature. Our study compar...
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Article
Open AccessGoodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago
Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally us...
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Chapter and Conference Paper
Automatic Detection of Sympathovagal Response Using HRV Analysis. Case Study: Resident Surgeons During Training and Their First Laparoscopic Surgery
Monitoring the physiological response during training can provide valuable information about how surgeons cope with the stress associated with this activity. Heart Rate Variability (HRV) analysis is a widely u...
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Article
Mechanical bowel preparation in elective colorectal surgery: a propensity score-matched analysis of the Italian colorectal anastomotic leakage (iCral) study group prospective cohorts
Retrospective evaluation of the effects of mechanical bowel preparation (MBP) on data derived from two prospective open-label observational multicenter studies in Italy regarding elective colorectal surgery. M...
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Article
Open AccessInterrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids
Approximately 20–50% of patients presenting with localized colorectal cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is a major prognostic determinant. Here, we have...
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Article
Origin invariant molecular orbital decomposition of optical rotation
Optical rotation (OR) is a sensitive electronic property for which there are no clear structure-property relations. We proposed an approach to decompose the OR tensor in terms of one-electron transitions betwe...
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Article
Open AccessTotal neoadjuvant therapy for the treatment of locally advanced rectal cancer: a systematic minireview
Colorectal carcinoma is the second leading cause of cancer-related deaths, and indeed, rectal cancer accounting for approximately one third of newly diagnosed patients. Gold standard in the treatment of rectal...
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Article
Open AccessRobotic versus transanal total mesorectal excision in sexual, anorectal, and urinary function: a multicenter, prospective, observational study
Improved long-term survival after low anterior resection (LAR) for rectal cancer highlights the importance of functional outcome. Urogenital and anorectal dysfunction is frequently reported after conventional ...
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Article
Management and 1-year outcomes of anastomotic leakage after elective colorectal surgery
To analyze different types of management and one-year outcomes of anastomotic leakage (AL) after elective colorectal resection.
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Article
Open AccessAge and comorbidities do not affect short-term outcomes after laparoscopic rectal cancer resection in elderly patients. A multi-institutional cohort study in 287 patients
Postoperative complications and mortality rates after rectal cancer surgery are higher in elderly than in non-elderly patients. The aim of this study is to evaluate whether, like in open surgery, age and comor...
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Article
What About Gastric Schwannoma? A Review Article
Gastric schwannomas (GSs) are rare mesenchymal neoplasms of the gastrointestinal tract. Diagnosis is often achieved postoperatively, based on pathology reports of retrieved specimens. The aim of the present st...
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Article
Colorectal surgery in Italy during the Covid19 outbreak: a survey from the iCral study group
The COVID19 pandemic had a deep impact on healthcare facilities in Italy, with profound reorganization of surgical activities. The Italian ColoRectal Anastomotic Leakage (iCral) study group collecting 43 Itali...
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Article
Correction to: Skin bridge loop stoma: outcome in 45 patients in comparison with stoma made on a plastic rod
The name of the author was incorrectly spelled as “Filippo Carannant”. The correct spelling is “Filippo Carannante” and is now presented correctly in this article.
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Article
Impact of Ethnicity on the Prevalence of Early Repolarization Pattern in Children: Comparison Between Caucasian and African Populations
The patterns and prevalence of early repolarization pattern (ER) in pediatric populations from ethnic backgrounds other than Caucasian have not been determined. Black African children (ages 4–12) from north-we...
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Article
Skin bridge loop stoma: outcome in 45 patients in comparison with stoma made on a plastic rod
Loop stoma reduces the complications related to anastomotic leak. The skin bridge loop stoma is a recently described technique with many potential advantages over the current technique involving a plastic rod....
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Article
Open AccessProof-of-concept Raman spectroscopy study aimed to differentiate thyroid follicular patterned lesions
Inter-observer variability and cancer over-diagnosis are emerging clinical problems, especially for follicular patterned thyroid lesions. This challenge strongly calls for a new clinical tool to reliably ident...
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Article
Open AccessRAMAN spectroscopy imaging improves the diagnosis of papillary thyroid carcinoma
Recent investigations strongly suggest that Raman spectroscopy (RS) can be used as a clinical tool in cancer diagnosis to improve diagnostic accuracy. In this study, we evaluated the efficiency of Raman imagin...
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Article
Open AccessIpilimumab and immune-mediated adverse events: a case report of anti-CTLA4 induced ileitis
Ipilimumab is a fully human monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 , a key negative regulator of T-cell activation approved by the Food and Drug Administration as of March 2011 f...
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Article
Serum lactate dehydrogenase alone is not a helpful prognostic factor in resected colorectal cancer patients
Several studies showed how serum levels of lactate dehydrogenase (LDH) are related with a worse prognosis and response to therapy. Its role in colorectal cancer is not still assessed. The aim of this study was...
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Article
Polystyrene-based self-aggregating polymers based on UPy units
The synthesis and characterization of a series of polystyrene (PS)-based copolymers, bearing 2-ureido-4[1H]-pyrimidinone (UPy) units pendant from the polymer backbone, is reported. The PS-based copolymers are eff...